Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2782878..2783382 Replicon chromosome
Accession NC_019776
Organism Cyanobacterium aponinum PCC 10605

Toxin (Protein)


Gene name yoeB Uniprot ID K9Z6P1
Locus tag CYAN10605_RS11630 Protein ID WP_015220141.1
Coordinates 2782878..2783135 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID K9Z7P3
Locus tag CYAN10605_RS11635 Protein ID WP_015220142.1
Coordinates 2783119..2783382 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYAN10605_RS11605 2778033..2778149 + 117 WP_015220136.1 cytochrome b6-f complex subunit PetG -
CYAN10605_RS11610 2778251..2779672 + 1422 WP_015220137.1 deoxyribodipyrimidine photo-lyase -
CYAN10605_RS11615 2780271..2781044 - 774 WP_015220138.1 DUF4114 domain-containing protein -
CYAN10605_RS11620 2781403..2782095 + 693 WP_015220139.1 sugar transferase -
CYAN10605_RS11625 2782164..2782853 + 690 WP_015220140.1 glycoside hydrolase family protein -
CYAN10605_RS11630 2782878..2783135 - 258 WP_015220141.1 Txe/YoeB family addiction module toxin Toxin
CYAN10605_RS11635 2783119..2783382 - 264 WP_015220142.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CYAN10605_RS11640 2783586..2785004 + 1419 WP_015220143.1 GTP-binding protein -
CYAN10605_RS11645 2785277..2786188 - 912 WP_015220144.1 cation diffusion facilitator family transporter -
CYAN10605_RS11650 2786360..2786539 + 180 WP_015220145.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(22-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10126.75 Da        Isoelectric Point: 10.4283

>T28605 WP_015220141.1 NC_019776:c2783135-2782878 [Cyanobacterium aponinum PCC 10605]
MTWKIEFSRNTLKDAKKLKSAKLDGNLKELLNILKSNPYEPPYEKLSGNLKGYYSRRINIKHRLVYRVDDNNKTIKILSV
WSHYE

Download         Length: 258 bp

>T28605 NC_019776:c2783135-2782878 [Cyanobacterium aponinum PCC 10605]
ATGACTTGGAAGATTGAATTTAGTCGAAATACTCTAAAAGATGCGAAAAAACTCAAATCAGCAAAATTAGACGGTAATCT
CAAAGAATTACTCAACATCTTAAAATCAAATCCCTATGAGCCTCCTTACGAAAAATTATCAGGTAATTTAAAAGGTTACT
ATTCAAGGAGAATAAATATTAAGCATCGCCTAGTTTATCGTGTTGATGACAATAATAAAACCATCAAAATTCTTTCTGTC
TGGTCTCATTATGAATAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9983.19 Da        Isoelectric Point: 4.2571

>AT28605 WP_015220142.1 NC_019776:c2783382-2783119 [Cyanobacterium aponinum PCC 10605]
MKIINISTARNNLFSLIEQVNQDHHPRIISSKKGDVVILSKEDWDSLQETLYLQSIPNLVSSIKTAEKDNEWVSEEEFLG
VLNDLED

Download         Length: 264 bp

>AT28605 NC_019776:c2783382-2783119 [Cyanobacterium aponinum PCC 10605]
ATGAAAATAATTAATATAAGTACTGCAAGAAATAATTTATTCAGTCTAATAGAACAAGTGAATCAAGATCATCATCCTCG
GATTATCAGCAGTAAAAAAGGGGATGTCGTAATCTTATCAAAAGAAGACTGGGACAGTTTACAAGAAACCTTGTATTTAC
AATCTATTCCTAACTTAGTCTCATCCATAAAAACAGCAGAAAAAGATAATGAATGGGTATCAGAGGAGGAATTTTTGGGG
GTTTTAAATGACTTGGAAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A844GUR9

Antitoxin

Source ID Structure
AlphaFold DB A0A844GUQ0

References