Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1844559..1844976 Replicon chromosome
Accession NZ_LN681227
Organism Xenorhabdus nematophila AN6/1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag XNC2_RS08255 Protein ID WP_013184145.1
Coordinates 1844559..1844732 (-) Length 58 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID N1NP74
Locus tag XNC2_RS08260 Protein ID WP_010847387.1
Coordinates 1844722..1844976 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XNC2_RS08235 1839900..1840484 + 585 WP_143767639.1 manganese efflux pump MntP -
XNC2_RS08240 1840594..1841415 - 822 WP_041573672.1 23S rRNA (guanine(745)-N(1))-methyltransferase -
XNC2_RS08245 1841699..1843027 - 1329 WP_010847384.1 MFS transporter -
XNC2_RS08250 1843036..1844559 - 1524 WP_013184144.1 signal transduction histidine-protein kinase/phosphatase UhpB -
XNC2_RS08255 1844559..1844732 - 174 WP_013184145.1 toxin-antitoxin system protein Toxin
XNC2_RS08260 1844722..1844976 - 255 WP_010847387.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
XNC2_RS08265 1845416..1845796 + 381 WP_113967564.1 transposase -
XNC2_RS08270 1845802..1846419 - 618 WP_010847389.1 transcriptional regulator UhpA -
XNC2_RS08275 1846561..1847937 - 1377 WP_010847390.1 hexose-6-phosphate:phosphate antiporter -
XNC2_RS08280 1848544..1848879 - 336 WP_013184149.1 hypothetical protein -
XNC2_RS08285 1849265..1849954 + 690 WP_010847392.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-74)


Sequences

Toxin        


Download         Length: 58 a.a.        Molecular weight: 6973.13 Da        Isoelectric Point: 10.1541

>T285552 WP_013184145.1 NZ_LN681227:c1844732-1844559 [Xenorhabdus nematophila AN6/1]
MIFNIEFDERAVKEWQKLDNSIREQFKKKLKKLQKNPYIEPARLHGDLACFLRNFSF

Download         Length: 174 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9831.21 Da        Isoelectric Point: 4.7025

>AT285552 WP_010847387.1 NZ_LN681227:c1844976-1844722 [Xenorhabdus nematophila AN6/1]
MSTIQIRVDEELKKSAYQAFDKLNLSPSDAMRLFLRYVAEHEKLPFTEVSVMVAEHDEDEDILDVVRDRLKNPAKRIRVN
LDDI

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB N1NP74

References