Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1871897..1872168 Replicon chromosome
Accession NZ_LM995446
Organism Escherichia coli strain K-12 substr. RV308

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1871935..1872038 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1871897..1872168 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECRV308_RS09365 1869054..1870493 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECRV308_RS09370 1870611..1870847 + 237 WP_001295499.1 DUF1480 family protein -
ECRV308_RS09375 1870952..1871143 + 192 WP_000457842.1 YebW family protein -
ECRV308_RS09380 1871144..1871800 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1871897..1872168 + 272 - - Antitoxin
- 1871935..1872038 - 104 - - Toxin
ECRV308_RS09390 1872196..1872537 - 342 WP_000976476.1 YebY family protein -
ECRV308_RS09395 1872550..1873422 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
ECRV308_RS09400 1873426..1873800 - 375 WP_000168747.1 CopC domain-containing protein YobA -
ECRV308_RS09405 1873939..1874169 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECRV308_RS09410 1874271..1874927 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
ECRV308_RS09415 1874951..1875613 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T285436 NZ_LM995446:c1872038-1871935 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT285436 NZ_LM995446:1871897-1872168 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References