Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 1754749..1755314 Replicon chromosome
Accession NZ_HG992749
Organism Vibrio sp. B1FLJ16

Toxin (Protein)


Gene name relE Uniprot ID A0A7X8U0A9
Locus tag KHN79_RS07970 Protein ID WP_029865673.1
Coordinates 1754749..1755036 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KHN79_RS07975 Protein ID WP_017420803.1
Coordinates 1755033..1755314 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHN79_RS07950 (ACOMICROBIO_LOCUS1172) 1751121..1751813 + 693 WP_182011762.1 NAD(P)H-binding protein -
KHN79_RS07955 (ACOMICROBIO_LOCUS1173) 1752003..1753382 + 1380 WP_182011761.1 L-cystine transporter -
KHN79_RS07960 (ACOMICROBIO_FLGHMIGD_01612) 1753742..1754095 - 354 WP_182011760.1 DUF1428 domain-containing protein -
KHN79_RS07965 1754219..1754350 + 132 Protein_1537 IS110 family transposase -
KHN79_RS07970 (ACOMICROBIO_FLGHMIGD_01613) 1754749..1755036 - 288 WP_029865673.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KHN79_RS07975 (ACOMICROBIO_LOCUS1174) 1755033..1755314 - 282 WP_017420803.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KHN79_RS21600 1755405..1755515 - 111 WP_244812636.1 DUF3265 domain-containing protein -
KHN79_RS07980 (ACOMICROBIO_FLGHMIGD_01615) 1755512..1756213 - 702 WP_182011759.1 hypothetical protein -
KHN79_RS07990 (ACOMICROBIO_FLGHMIGD_01616) 1756375..1757034 - 660 WP_182011767.1 hypothetical protein -
KHN79_RS07995 (ACOMICROBIO_LOCUS1175) 1757297..1757836 - 540 WP_244812548.1 class I SAM-dependent methyltransferase -
KHN79_RS08000 (ACOMICROBIO_LOCUS1176) 1757967..1758938 - 972 WP_182011757.1 HNH endonuclease -
KHN79_RS08005 (ACOMICROBIO_LOCUS1177) 1759085..1759465 - 381 WP_182011766.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10993.65 Da        Isoelectric Point: 5.1098

>T285276 WP_029865673.1 NZ_HG992749:c1755036-1754749 [Vibrio sp. B1FLJ16]
MKVVWSPLALQKLGDAAEFISLDNPSAAEKWVNEVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILSEDDV

Download         Length: 288 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10354.90 Da        Isoelectric Point: 7.0141

>AT285276 WP_017420803.1 NZ_HG992749:c1755314-1755033 [Vibrio sp. B1FLJ16]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
ADARAQVLGRIKK

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X8U0A9

Antitoxin

Source ID Structure

References