Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 4543994..4544603 Replicon chromosome
Accession NC_019676
Organism Nostoc sp. PCC 7107

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NOS7107_RS19385 Protein ID WP_015114644.1
Coordinates 4544241..4544603 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID K9QH00
Locus tag NOS7107_RS19380 Protein ID WP_015114643.1
Coordinates 4543994..4544251 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOS7107_RS19360 4539440..4540237 + 798 WP_015114639.1 5'/3'-nucleotidase SurE -
NOS7107_RS19365 4540623..4541519 + 897 WP_015114640.1 MBL fold metallo-hydrolase -
NOS7107_RS19370 4541836..4542894 + 1059 WP_044500159.1 bifunctional riboflavin kinase/FAD synthetase -
NOS7107_RS19375 4543003..4543911 + 909 WP_015114642.1 MoxR family ATPase -
NOS7107_RS19380 4543994..4544251 + 258 WP_015114643.1 hypothetical protein Antitoxin
NOS7107_RS19385 4544241..4544603 + 363 WP_015114644.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NOS7107_RS19390 4544683..4546440 - 1758 WP_015114645.1 iron uptake porin -
NOS7107_RS19395 4546813..4547094 - 282 WP_015114646.1 4a-hydroxytetrahydrobiopterin dehydratase -
NOS7107_RS19400 4547126..4547731 - 606 WP_015114647.1 hypothetical protein -
NOS7107_RS19405 4548252..4549310 - 1059 WP_015113285.1 photosystem II D2 protein (photosystem q(a) protein) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13792.47 Da        Isoelectric Point: 4.7712

>T28496 WP_015114644.1 NC_019676:4544241-4544603 [Nostoc sp. PCC 7107]
MQSNNPVSMRFSDEFEEQLYKLSKRFRNIRSDVQPIIEELQQGNIVGDGIGRIGEEYVVYKVRVRNSNIQKGKSAGYRLI
YQLESPTSILLLTIYAKSDREDIGANEIRDIVANFDSEES

Download         Length: 363 bp

>T28496 NC_019676:4544241-4544603 [Nostoc sp. PCC 7107]
ATGCAGAGTAATAATCCGGTGTCAATGAGGTTCTCAGATGAGTTTGAGGAGCAACTTTACAAACTCTCAAAAAGATTTCG
CAATATTCGTTCTGATGTGCAACCAATTATTGAGGAACTACAGCAAGGAAATATAGTCGGAGACGGAATTGGGCGTATTG
GTGAGGAGTACGTTGTTTATAAGGTGAGAGTTCGCAATAGTAATATTCAAAAAGGTAAAAGTGCTGGATATCGCTTAATT
TATCAACTTGAGTCACCTACAAGTATTTTGTTACTCACAATTTATGCCAAATCTGACCGAGAAGATATTGGTGCAAATGA
AATTCGAGATATTGTAGCTAATTTTGATAGTGAAGAAAGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9584.86 Da        Isoelectric Point: 4.1962

>AT28496 WP_015114643.1 NC_019676:4543994-4544251 [Nostoc sp. PCC 7107]
MKAIEVTGKIDSEGNLILDQPIREITYPYQVRVIVLVPEPTAAEEIDPDDTPVEEIKASLRRALQQAKTGQTRPISELWD
RIDAE

Download         Length: 258 bp

>AT28496 NC_019676:4543994-4544251 [Nostoc sp. PCC 7107]
ATGAAAGCGATCGAAGTAACTGGCAAAATTGACTCTGAAGGAAACTTAATTTTAGATCAGCCGATTCGGGAAATCACTTA
TCCTTATCAAGTGCGGGTGATTGTGTTAGTTCCAGAACCCACAGCAGCAGAAGAAATTGATCCTGATGATACACCCGTTG
AAGAAATTAAAGCCAGCTTAAGGAGGGCTTTACAGCAAGCTAAAACGGGTCAAACTAGACCAATTAGTGAGCTATGGGAC
AGGATTGATGCAGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB K9QH00

References