Detailed information of TA system TA284459

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 195373..195595
• Replicon: chromosome
• Accession: NZ_CP128255
• Organism: Escherichia coli strain T309.Ta3

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: QRX22_RS00945
• Protein ID: WP_001295224.1
• Coordinates: 195488..195595 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	195373..195431 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QRX22_RS00925	190814..191716	+	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-
QRX22_RS00930	191727..192710	+	984	WP_021531678.1	dipeptide ABC transporter ATP-binding protein	-
QRX22_RS00935	192707..193711	+	1005	WP_000103570.1	dipeptide ABC transporter ATP-binding subunit DppF	-
QRX22_RS00940	193741..195012	-	1272	WP_014640225.1	aromatic amino acid transport family protein	-
-	195373..195431	-	59	-	-	Antitoxin
QRX22_RS00945	195488..195595	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
QRX22_RS00950	195682..197361	-	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
QRX22_RS00955	197358..197549	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
QRX22_RS00960	197546..199117	-	1572	WP_001204945.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
QRX22_RS00965	199390..199578	+	189	WP_001063314.1	cellulose biosynthesis protein BcsR	-
QRX22_RS00970	199590..200342	+	753	Protein_191	cellulose biosynthesis protein BcsQ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T284459 WP_001295224.1 NZ_CP128255:195488-195595 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 59 bp

>AT284459 NZ_CP128255:c195431-195373 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin