Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 56770..57332 Replicon plasmid pVFBJ05
Accession NZ_CP128206
Organism Vibrio furnissii strain VFBJ05

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QSU95_RS23435 Protein ID WP_038152854.1
Coordinates 57030..57332 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag QSU95_RS23430 Protein ID WP_004729600.1
Coordinates 56770..57015 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSU95_RS23415 (QSU95_23415) 54355..54582 - 228 WP_038152853.1 hypothetical protein -
QSU95_RS23420 (QSU95_23420) 54812..55732 + 921 WP_202644000.1 IS5 family transposase -
QSU95_RS23425 (QSU95_23425) 56033..56569 - 537 Protein_51 recombinase family protein -
QSU95_RS23430 (QSU95_23430) 56770..57015 + 246 WP_004729600.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QSU95_RS23435 (QSU95_23435) 57030..57332 + 303 WP_038152854.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QSU95_RS23440 (QSU95_23440) 57329..57931 - 603 WP_004729602.1 recombinase family protein -
QSU95_RS23445 (QSU95_23445) 58541..59617 - 1077 WP_038152856.1 replication initiation protein -
QSU95_RS23450 (QSU95_23450) 60561..61283 + 723 WP_004729604.1 hypothetical protein -
QSU95_RS23455 (QSU95_23455) 61273..62022 + 750 WP_119299138.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid sul2 / aph(3'')-Ib / aph(6)-Id / tet(A) / floR - 1..85626 85626
- flank IS/Tn - - 54812..55732 920


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-56)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11644.32 Da        Isoelectric Point: 6.7572

>T284406 WP_038152854.1 NZ_CP128206:57030-57332 [Vibrio furnissii]
MSSYKLSPLAQSDLTDIRRYTIEHWGSTQWSVYFNELQESMSLLASNELIGIQIPEMGERYYRFPLKHHVIYYITQEDHI
VIVAVLGKHMSPAKHFASIS

Download         Length: 303 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9115.57 Da        Isoelectric Point: 4.5702

>AT284406 WP_004729600.1 NZ_CP128206:56770-57015 [Vibrio furnissii]
MQSLTANTAKTKFGDLLMKVQREPVQISKNGSPVAVMMSCEEYEQLEALKMMLVKSRFEQAEIDIRNGDLVDGDEFMKSL
A

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References