Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 104618..105153 Replicon plasmid pELP1.10
Accession NZ_CP127882
Organism Serratia marcescens strain ELP1.10

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QRD25_RS24370 Protein ID WP_164058116.1
Coordinates 104618..104905 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QRD25_RS24375 Protein ID WP_164058115.1
Coordinates 104902..105153 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRD25_RS24340 (QRD25_24350) 100082..100482 - 401 Protein_86 transposase -
QRD25_RS24345 (QRD25_24355) 100571..100774 + 204 Protein_87 hypothetical protein -
QRD25_RS24350 (QRD25_24360) 100910..101056 + 147 Protein_88 DNA polymerase V subunit UmuC -
QRD25_RS24355 (QRD25_24365) 101647..102426 + 780 WP_286094250.1 hypothetical protein -
QRD25_RS24360 (QRD25_24370) 102700..103032 - 333 WP_286094251.1 hypothetical protein -
QRD25_RS24365 (QRD25_24375) 103123..103527 - 405 WP_286094252.1 hypothetical protein -
QRD25_RS24370 (QRD25_24380) 104618..104905 - 288 WP_164058116.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QRD25_RS24375 (QRD25_24385) 104902..105153 - 252 WP_164058115.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QRD25_RS24380 (QRD25_24390) 105268..105945 - 678 Protein_94 plasmid SOS inhibition protein A -
QRD25_RS24385 (QRD25_24395) 105990..106430 - 441 WP_286094253.1 conjugation system SOS inhibitor PsiB -
QRD25_RS24390 (QRD25_24400) 106473..108524 - 2052 WP_286094254.1 ParB N-terminal domain-containing protein -
QRD25_RS24395 (QRD25_24405) 108618..108908 - 291 WP_197761722.1 ribulokinase -
QRD25_RS24400 (QRD25_24410) 109450..110085 + 636 WP_019454356.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..129237 129237
- flank IS/Tn - - 100082..100354 272


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10887.98 Da        Isoelectric Point: 10.2278

>T284345 WP_164058116.1 NZ_CP127882:c104905-104618 [Serratia marcescens]
VMYTIKFRESALKEWGKLDKALQQQFAKKLKKCCENPHIPSAKLRGMPGCYKIKLRASGFRLVYEVIDDCLIIAVVAVGK
RERGDVYQLASERLK

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9168.39 Da        Isoelectric Point: 3.9015

>AT284345 WP_164058115.1 NZ_CP127882:c105153-104902 [Serratia marcescens]
MPNIILSDTSASISELKKNPMETVGAGDGFPVAILNRNQPAFYCVPAALYEQMLDAIDDQELVRLVNERRSEALVDIDLD
QFA

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References