Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-ArgA
Location 4722439..4723258 Replicon chromosome
Accession NZ_CP127873
Organism Klebsiella michiganensis strain ELP1.34B

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag QRD21_RS22095 Protein ID WP_004110819.1
Coordinates 4723001..4723258 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag QRD21_RS22090 Protein ID WP_286114672.1
Coordinates 4722439..4722990 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRD21_RS22070 (QRD21_22070) 4718661..4719569 - 909 WP_286114669.1 transcriptional regulator GcvA -
QRD21_RS22075 (QRD21_22075) 4719690..4720577 + 888 WP_286114670.1 DMT family transporter -
QRD21_RS22080 (QRD21_22080) 4720793..4721539 - 747 WP_286116471.1 class I SAM-dependent methyltransferase -
QRD21_RS22085 (QRD21_22085) 4721969..4722325 - 357 Protein_4347 class I SAM-dependent methyltransferase -
QRD21_RS22090 (QRD21_22090) 4722439..4722990 - 552 WP_286114672.1 N-acetyltransferase Antitoxin
QRD21_RS22095 (QRD21_22095) 4723001..4723258 - 258 WP_004110819.1 YjhX family toxin Toxin
QRD21_RS22100 (QRD21_22100) 4723934..4725118 + 1185 WP_048261308.1 mannonate dehydratase -
QRD21_RS22105 (QRD21_22105) 4725192..4726667 + 1476 WP_286114674.1 fructuronate reductase -
QRD21_RS22110 (QRD21_22110) 4726806..4727582 + 777 WP_004847986.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(22-130)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T284327 WP_004110819.1 NZ_CP127873:c4723258-4723001 [Klebsiella michiganensis]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20034.81 Da        Isoelectric Point: 6.3270

>AT284327 WP_286114672.1 NZ_CP127873:c4722990-4722439 [Klebsiella michiganensis]
MTNHSFTFHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGVGVGGELIRHGIEQLKAMGSQAVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPEAHKACWMLQPISS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References