Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2025691..2025962 Replicon chromosome
Accession NZ_CP127848
Organism Escherichia coli strain MB7671

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2025821..2025924 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2025691..2025962 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJZ59_RS09695 2022246..2022908 - 663 WP_000944256.1 exodeoxyribonuclease X -
PJZ59_RS09700 2022932..2023588 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
PJZ59_RS09705 2023690..2023920 - 231 WP_000916763.1 DNA polymerase III subunit theta -
PJZ59_RS09710 2024059..2024433 + 375 WP_000204699.1 CopC domain-containing protein YobA -
PJZ59_RS09715 2024437..2025309 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
PJZ59_RS09720 2025322..2025663 + 342 WP_000976492.1 YebY family protein -
- 2025691..2025962 - 272 - - Antitoxin
- 2025821..2025924 + 104 - - Toxin
PJZ59_RS09725 2026059..2026715 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
PJZ59_RS09730 2026716..2026907 - 192 WP_001296140.1 YebW family protein -
PJZ59_RS09735 2027012..2027248 - 237 WP_001295499.1 YebV family protein -
PJZ59_RS09740 2027366..2028805 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T284283 NZ_CP127848:2025821-2025924 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT284283 NZ_CP127848:c2025962-2025691 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References