Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1608619..1609163 Replicon chromosome
Accession NZ_CP127390
Organism Propionimicrobium sp. PCR01-08-3

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QQ658_RS07350 Protein ID WP_286026999.1
Coordinates 1608858..1609163 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QQ658_RS07345 Protein ID WP_286026998.1
Coordinates 1608619..1608852 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ658_RS07325 (QQ658_07325) 1603913..1605070 - 1158 WP_286026994.1 homoserine O-acetyltransferase -
QQ658_RS07330 (QQ658_07330) 1605087..1606388 - 1302 WP_286026995.1 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase -
QQ658_RS07335 (QQ658_07335) 1606476..1607483 - 1008 WP_286026996.1 ABC transporter substrate-binding protein -
QQ658_RS07340 (QQ658_07340) 1607494..1608309 - 816 WP_286026997.1 ABC transporter permease -
QQ658_RS07345 (QQ658_07345) 1608619..1608852 + 234 WP_286026998.1 antitoxin Antitoxin
QQ658_RS07350 (QQ658_07350) 1608858..1609163 + 306 WP_286026999.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QQ658_RS07355 (QQ658_07355) 1609207..1610739 - 1533 WP_286027000.1 DHA2 family efflux MFS transporter permease subunit -
QQ658_RS07360 (QQ658_07360) 1610883..1612337 - 1455 WP_286027001.1 MFS transporter -
QQ658_RS07365 (QQ658_07365) 1612392..1613702 - 1311 WP_286027002.1 MATE family efflux transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11136.94 Da        Isoelectric Point: 5.7783

>T284235 WP_286026999.1 NZ_CP127390:1608858-1609163 [Propionimicrobium sp. PCR01-08-3]
MRPIYLARLDKTRPVLVLTRELVRPYLNSVTVAPITSTIRGLSTELPVGSRNGLDHDCVVSLDNIVTITVKDLGRQIGFL
LPDQEGNLTEAMMNAFDLVTS

Download         Length: 306 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8564.62 Da        Isoelectric Point: 4.7596

>AT284235 WP_286026998.1 NZ_CP127390:1608619-1608852 [Propionimicrobium sp. PCR01-08-3]
MSMQIAVRLPDELAQFVDAEVTAGHAPSRAAVVTRALEREQRYRAALADIEILKNTQPDDDFDALARHAAHRPLDLD

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References