Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 334653..335161 Replicon chromosome
Accession NZ_CP127390
Organism Propionimicrobium sp. PCR01-08-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QQ658_RS01605 Protein ID WP_286025943.1
Coordinates 334901..335161 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QQ658_RS01600 Protein ID WP_286025942.1
Coordinates 334653..334904 (+) Length 84 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ658_RS01580 (QQ658_01580) 330182..330955 - 774 WP_286025938.1 ABC transporter permease -
QQ658_RS01585 (QQ658_01585) 330963..331769 - 807 WP_286025939.1 ATP-binding cassette domain-containing protein -
QQ658_RS01590 (QQ658_01590) 331973..332635 - 663 WP_286025940.1 CatB-related O-acetyltransferase -
QQ658_RS01595 (QQ658_01595) 332801..334450 - 1650 WP_286025941.1 ABC-F family ATP-binding cassette domain-containing protein -
QQ658_RS01600 (QQ658_01600) 334653..334904 + 252 WP_286025942.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QQ658_RS01605 (QQ658_01605) 334901..335161 + 261 WP_286025943.1 Txe/YoeB family addiction module toxin Toxin
QQ658_RS01610 (QQ658_01610) 335409..336764 - 1356 WP_286025944.1 C1 family peptidase -
QQ658_RS01615 (QQ658_01615) 337070..338533 + 1464 WP_286025945.1 Nramp family divalent metal transporter -
QQ658_RS01620 (QQ658_01620) 338631..339044 - 414 WP_286025946.1 DUF1801 domain-containing protein -
QQ658_RS01625 (QQ658_01625) 339276..339527 + 252 WP_286025947.1 addiction module protein -
QQ658_RS01630 (QQ658_01630) 339524..339844 + 321 WP_286025948.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-84)

Antitoxin

(1-72)


Sequences


Toxin        


Download         Length: 87 a.a.        Molecular weight: 10066.54 Da        Isoelectric Point: 8.9165

>T284231 WP_286025943.1 NZ_CP127390:334901-335161 [Propionimicrobium sp. PCR01-08-3]
VKLVITANGWNDYCHWQETDRATLKRVNKLIDAAMRTPKDGIGKPEALKYQLGEVWSRRITEEHRLVYRIGDAEIIILQA
RFHYDA

Download         Length: 261 bp


Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9111.09 Da        Isoelectric Point: 5.0368

>AT284231 WP_286025942.1 NZ_CP127390:334653-334904 [Propionimicrobium sp. PCR01-08-3]
MSTISASTARRELFPLIAEVNEDHTEVRITSKAGNAVLISEAEFEAWQTTRYLFSTKANAQHLLESLAQAAAGDVHSHDL
DRA

Download         Length: 252 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References