Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2618485..2618716 Replicon chromosome
Accession NZ_CP127314
Organism Escherichia coli strain C25

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2618613..2618715 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2618485..2618716 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRM69_RS12345 2615037..2615699 - 663 WP_000944256.1 exodeoxyribonuclease X -
QRM69_RS12350 2615723..2616379 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
QRM69_RS12355 2616482..2616712 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QRM69_RS12360 2616851..2617225 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QRM69_RS12365 2617229..2618101 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
QRM69_RS12370 2618114..2618455 + 342 WP_000984819.1 YebY family protein -
- 2618485..2618716 - 232 - - Antitoxin
- 2618613..2618715 + 103 - - Toxin
QRM69_RS12375 2618847..2619923 - 1077 WP_286005063.1 phage integrase Arm DNA-binding domain-containing protein -
QRM69_RS12380 2619889..2620170 - 282 WP_001311878.1 excisionase -
QRM69_RS12385 2620277..2620465 - 189 WP_024165285.1 DUF1187 family protein -
- 2620281..2620459 + 179 NuclAT_0 - -
- 2620281..2620459 + 179 NuclAT_0 - -
- 2620281..2620459 + 179 NuclAT_0 - -
- 2620281..2620459 + 179 NuclAT_0 - -
QRM69_RS12390 2620458..2620652 - 195 WP_010989194.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
QRM69_RS12395 2620716..2621768 - 1053 WP_021517972.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2612980..2663693 50713


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T284143 NZ_CP127314:2618613-2618715 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 232 bp

>AT284143 NZ_CP127314:c2618716-2618485 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References