Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
Location | 2618485..2618716 | Replicon | chromosome |
Accession | NZ_CP127314 | ||
Organism | Escherichia coli strain C25 |
Toxin (RNA)
Gene name | SdsR | ||
Locus tag | - | ||
Coordinates | 2618613..2618715 (+) |
Antitoxin (RNA)
Gene name | RyeA | ||
Locus tag | - | ||
Coordinates | 2618485..2618716 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QRM69_RS12345 | 2615037..2615699 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
QRM69_RS12350 | 2615723..2616379 | - | 657 | WP_000011644.1 | carbon-nitrogen hydrolase family protein YobB | - |
QRM69_RS12355 | 2616482..2616712 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
QRM69_RS12360 | 2616851..2617225 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
QRM69_RS12365 | 2617229..2618101 | + | 873 | WP_000879311.1 | copper homeostasis membrane protein CopD | - |
QRM69_RS12370 | 2618114..2618455 | + | 342 | WP_000984819.1 | YebY family protein | - |
- | 2618485..2618716 | - | 232 | - | - | Antitoxin |
- | 2618613..2618715 | + | 103 | - | - | Toxin |
QRM69_RS12375 | 2618847..2619923 | - | 1077 | WP_286005063.1 | phage integrase Arm DNA-binding domain-containing protein | - |
QRM69_RS12380 | 2619889..2620170 | - | 282 | WP_001311878.1 | excisionase | - |
QRM69_RS12385 | 2620277..2620465 | - | 189 | WP_024165285.1 | DUF1187 family protein | - |
- | 2620281..2620459 | + | 179 | NuclAT_0 | - | - |
- | 2620281..2620459 | + | 179 | NuclAT_0 | - | - |
- | 2620281..2620459 | + | 179 | NuclAT_0 | - | - |
- | 2620281..2620459 | + | 179 | NuclAT_0 | - | - |
QRM69_RS12390 | 2620458..2620652 | - | 195 | WP_010989194.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
QRM69_RS12395 | 2620716..2621768 | - | 1053 | WP_021517972.1 | RecT family recombinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2612980..2663693 | 50713 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T284143 NZ_CP127314:2618613-2618715 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 232 bp
>AT284143 NZ_CP127314:c2618716-2618485 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT