Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1433792..1434307 Replicon chromosome
Accession NZ_CP126969
Organism Corynebacterium sp. R4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QP027_RS07065 Protein ID WP_284823606.1
Coordinates 1434053..1434307 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QP027_RS07060 Protein ID WP_284823604.1
Coordinates 1433792..1434046 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP027_RS07030 (QP027_07030) 1429106..1429453 - 348 WP_284823594.1 50S ribosomal protein L19 -
QP027_RS07035 (QP027_07035) 1429696..1431978 - 2283 WP_284823596.1 Tex family protein -
QP027_RS07040 (QP027_07040) 1432077..1432439 + 363 WP_284823598.1 SdpI family protein -
QP027_RS07045 (QP027_07045) 1432442..1432786 + 345 WP_284823599.1 GntR family transcriptional regulator -
QP027_RS07050 (QP027_07050) 1432783..1432950 + 168 WP_284823601.1 hypothetical protein -
QP027_RS07055 (QP027_07055) 1432977..1433693 + 717 WP_284823602.1 hypothetical protein -
QP027_RS07060 (QP027_07060) 1433792..1434046 + 255 WP_284823604.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QP027_RS07065 (QP027_07065) 1434053..1434307 + 255 WP_284823606.1 Txe/YoeB family addiction module toxin Toxin
QP027_RS07070 (QP027_07070) 1434335..1435561 - 1227 WP_284823608.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
QP027_RS07075 (QP027_07075) 1435590..1436501 - 912 WP_284823610.1 class C sortase -
QP027_RS07080 (QP027_07080) 1436521..1437402 - 882 WP_284823612.1 SpaH/EbpB family LPXTG-anchored major pilin -
QP027_RS07085 (QP027_07085) 1437406..1438323 - 918 WP_284823614.1 class C sortase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10052.41 Da        Isoelectric Point: 8.8077

>T283412 WP_284823606.1 NZ_CP126969:1434053-1434307 [Corynebacterium sp. R4]
VVLSWSTHGWVDYLYWQSTDKKVLKRINTLIKDIPRNGHEGIGKPEPLKHEFSGYWSRRITDEHRLVYSYAEDSIVILSC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9712.88 Da        Isoelectric Point: 5.1312

>AT283412 WP_284823604.1 NZ_CP126969:1433792-1434046 [Corynebacterium sp. R4]
MKTISYTESRKRYAEVLDHVTDNREPVIVTRAGHESVVVMALDDFNSMQETAYLMRSPRNAQRLFESLEEVRSGKTTPHD
LIED

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References