Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 869144..869804 Replicon chromosome
Accession NZ_CP126325
Organism Salmonella enterica subsp. enterica strain HL21

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QN088_RS04190 Protein ID WP_058116119.1
Coordinates 869391..869804 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag QN088_RS04185 Protein ID WP_000351186.1
Coordinates 869144..869410 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN088_RS04165 (865072) 865072..866505 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
QN088_RS04170 (866664) 866664..866975 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
QN088_RS04175 (867139) 867139..867798 + 660 WP_284546204.1 hemolysin III family protein -
QN088_RS04180 (867914) 867914..868894 - 981 WP_023254245.1 tRNA-modifying protein YgfZ -
QN088_RS04185 (869144) 869144..869410 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
QN088_RS04190 (869391) 869391..869804 + 414 WP_058116119.1 protein YgfX Toxin
QN088_RS04195 (869857) 869857..870378 - 522 WP_001055885.1 flavodoxin FldB -
QN088_RS04200 (870491) 870491..871387 + 897 WP_000434299.1 site-specific tyrosine recombinase XerD -
QN088_RS04205 (871411) 871411..872124 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QN088_RS04210 (872130) 872130..873863 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16298.29 Da        Isoelectric Point: 11.1741

>T282767 WP_058116119.1 NZ_CP126325:869391-869804 [Salmonella enterica subsp. enterica]
VVLWQSDLRVSWRAQWISLLIHGLVSAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISRQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT282767 WP_000351186.1 NZ_CP126325:869144-869410 [Salmonella enterica subsp. enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References