Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | yeeUV (cbtA-cbeA)/CbtA-CbeA |
| Location | 539382..540062 | Replicon | chromosome |
| Accession | NZ_CP125781 | ||
| Organism | Trabulsiella odontotermitis strain TBY01 | ||
Toxin (Protein)
| Gene name | yeeV | Uniprot ID | - |
| Locus tag | QMG90_RS02655 | Protein ID | WP_283282598.1 |
| Coordinates | 539742..540062 (+) | Length | 107 a.a. |
Antitoxin (Protein)
| Gene name | yeeU | Uniprot ID | - |
| Locus tag | QMG90_RS02650 | Protein ID | WP_283282597.1 |
| Coordinates | 539382..539705 (+) | Length | 108 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG90_RS02620 (QMG90_02620) | 534411..535196 | + | 786 | WP_283282592.1 | hypothetical protein | - |
| QMG90_RS02625 (QMG90_02625) | 535414..535632 | - | 219 | WP_283283868.1 | AlpA family phage regulatory protein | - |
| QMG90_RS02630 (QMG90_02630) | 535724..536329 | - | 606 | WP_283282593.1 | inovirus Gp2 family protein | - |
| QMG90_RS02635 (QMG90_02635) | 536901..537857 | + | 957 | WP_283282594.1 | hypothetical protein | - |
| QMG90_RS02640 (QMG90_02640) | 538007..538828 | + | 822 | WP_283282595.1 | DUF932 domain-containing protein | - |
| QMG90_RS02645 (QMG90_02645) | 538899..539369 | + | 471 | WP_283282596.1 | DNA repair protein RadC | - |
| QMG90_RS02650 (QMG90_02650) | 539382..539705 | + | 324 | WP_283282597.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
| QMG90_RS02655 (QMG90_02655) | 539742..540062 | + | 321 | WP_283282598.1 | TA system toxin CbtA family protein | Toxin |
| QMG90_RS02660 (QMG90_02660) | 540176..540481 | + | 306 | Protein_520 | restriction endonuclease subunit M | - |
| QMG90_RS02665 (QMG90_02665) | 540544..541690 | + | 1147 | Protein_521 | IS3 family transposase | - |
| QMG90_RS02670 (QMG90_02670) | 541765..542163 | + | 399 | WP_283283869.1 | DUF1062 domain-containing protein | - |
| QMG90_RS02675 (QMG90_02675) | 542456..542821 | - | 366 | WP_283282599.1 | FaeA/PapI family transcriptional regulator | - |
| QMG90_RS02680 (QMG90_02680) | 542992..543729 | + | 738 | WP_283282600.1 | winged helix-turn-helix domain-containing protein | - |
| QMG90_RS02685 (QMG90_02685) | 543722..544189 | + | 468 | WP_283282601.1 | FidL-like protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 526917..544189 | 17272 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 107 a.a. Molecular weight: 12040.72 Da Isoelectric Point: 5.4654
>T282386 WP_283282598.1 NZ_CP125781:539742-540062 [Trabulsiella odontotermitis]
MHISTVPATVPVSSRLSPIQVWQQLLTYLLDHHYGLTLDDTPFHDDAAILEHIEAGITLADAVNFLVERYELVRIDRKGF
TWQEQTPFLTATDILRARRATGLINT
MHISTVPATVPVSSRLSPIQVWQQLLTYLLDHHYGLTLDDTPFHDDAAILEHIEAGITLADAVNFLVERYELVRIDRKGF
TWQEQTPFLTATDILRARRATGLINT
Download Length: 321 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|