Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2003161..2003305 Replicon chromosome
Accession NZ_CP124804
Organism Klebsiella variicola strain J57

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2003197..2003299 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2003161..2003305 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLG20_RS09765 (QLG20_09760) 1998291..2000351 + 2061 WP_124037874.1 oligopeptidase B -
QLG20_RS09770 (QLG20_09765) 2000355..2001014 - 660 WP_012541259.1 exodeoxyribonuclease X -
QLG20_RS09775 (QLG20_09770) 2001093..2001323 - 231 WP_012541260.1 DNA polymerase III subunit theta -
QLG20_RS09780 (QLG20_09775) 2001437..2001811 + 375 WP_012541261.1 CopC domain-containing protein YobA -
QLG20_RS09785 (QLG20_09780) 2001815..2002684 + 870 Protein_1911 copper homeostasis membrane protein CopD -
QLG20_RS09790 (QLG20_09785) 2002701..2003039 + 339 WP_008804271.1 YebY family protein -
- 2003161..2003305 - 145 - - Antitoxin
- 2003197..2003299 + 103 - - Toxin
QLG20_RS09795 (QLG20_09790) 2003684..2003827 - 144 WP_046881651.1 Ecr family regulatory small membrane protein -
QLG20_RS09800 (QLG20_09795) 2003931..2004899 - 969 WP_162493241.1 VirK/YbjX family protein -
QLG20_RS09805 (QLG20_09800) 2005056..2005709 + 654 WP_022066249.1 protein-serine/threonine phosphatase -
QLG20_RS09810 (QLG20_09805) 2005706..2005897 - 192 WP_002911395.1 YebW family protein -
QLG20_RS09815 (QLG20_09810) 2005995..2006234 - 240 WP_002911393.1 YebV family protein -
QLG20_RS09820 (QLG20_09815) 2006350..2007783 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T281227 NZ_CP124804:2003197-2003299 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT281227 NZ_CP124804:c2003305-2003161 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References