Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | ralRA/- |
| Location | 2167485..2167856 | Replicon | chromosome |
| Accession | NZ_CP123963 | ||
| Organism | Escherichia coli strain L6-21 | ||
Toxin (Protein)
| Gene name | ralR | Uniprot ID | F4VC37 |
| Locus tag | QC817_RS10590 | Protein ID | WP_001317028.1 |
| Coordinates | 2167662..2167856 (-) | Length | 65 a.a. |
Antitoxin (RNA)
| Gene name | ralA | ||
| Locus tag | - | ||
| Coordinates | 2167485..2167663 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QC817_RS10560 (2163237) | 2163237..2163410 | + | 174 | WP_001296046.1 | protein YnaL | - |
| QC817_RS10565 (2163440) | 2163440..2164813 | + | 1374 | WP_000123737.1 | ATP-dependent RNA helicase DbpA | - |
| QC817_RS10570 (2164942) | 2164942..2165877 | - | 936 | WP_001157407.1 | tRNA 2-thiocytidine(32) synthetase TtcA | - |
| QC817_RS10575 (2165929) | 2165929..2167164 | - | 1236 | WP_000040852.1 | site-specific integrase | - |
| QC817_RS10580 (2167166) | 2167166..2167381 | - | 216 | WP_000079604.1 | excisionase XisR | - |
| - (2167485) | 2167485..2167663 | + | 179 | NuclAT_0 | - | Antitoxin |
| - (2167485) | 2167485..2167663 | + | 179 | NuclAT_0 | - | Antitoxin |
| - (2167485) | 2167485..2167663 | + | 179 | NuclAT_0 | - | Antitoxin |
| - (2167485) | 2167485..2167663 | + | 179 | NuclAT_0 | - | Antitoxin |
| QC817_RS10585 (2167460) | 2167460..2167669 | - | 210 | WP_000276809.1 | double-strand break reduction protein RcbA | - |
| QC817_RS10590 (2167662) | 2167662..2167856 | - | 195 | WP_001317028.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
| QC817_RS10595 (2167913) | 2167913..2168722 | - | 810 | WP_000166319.1 | recombination protein RecT | - |
| QC817_RS10600 (2168715) | 2168715..2171315 | - | 2601 | WP_024232464.1 | exodeoxyribonuclease VIII | - |
| QC817_RS10605 (2171417) | 2171417..2171692 | - | 276 | WP_000632297.1 | protein RacC | - |
| QC817_RS10610 (2171767) | 2171767..2171937 | - | 171 | WP_001352098.1 | YdaE family protein | - |
| QC817_RS10615 (2171937) | 2171937..2172158 | - | 222 | WP_000560223.1 | killing protein KilR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7018.89 Da Isoelectric Point: 8.9538
>T279280 WP_001317028.1 NZ_CP123963:c2167856-2167662 [Escherichia coli]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
Download Length: 195 bp
>T279280 NZ_CP123963:c2167856-2167662 [Escherichia coli]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
Antitoxin
Download Length: 179 bp
>AT279280 NZ_CP123963:2167485-2167663 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
