Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2079617..2080271 Replicon chromosome
Accession NZ_CP123498
Organism Arsenophonus nasoniae strain aIh

Toxin (Protein)


Gene name cptA Uniprot ID A0A4P7L3M1
Locus tag QE207_RS12050 Protein ID WP_026821813.1
Coordinates 2079617..2080024 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A4P7KWA0
Locus tag QE207_RS12055 Protein ID WP_026821812.1
Coordinates 2080005..2080271 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE207_RS12035 (QE207_12025) 2075001..2076764 + 1764 WP_280628737.1 hypothetical protein -
QE207_RS12040 (QE207_12030) 2077284..2078597 + 1314 WP_280628738.1 S8 family serine peptidase -
QE207_RS12045 (QE207_12035) 2079083..2079601 + 519 WP_026821814.1 flavodoxin FldB -
QE207_RS12050 (QE207_12040) 2079617..2080024 - 408 WP_026821813.1 protein YgfX Toxin
QE207_RS12055 (QE207_12045) 2080005..2080271 - 267 WP_026821812.1 FAD assembly factor SdhE Antitoxin
QE207_RS12060 (QE207_12050) 2080531..2081517 + 987 WP_280628739.1 tRNA-modifying protein YgfZ -
QE207_RS12065 (QE207_12055) 2082372..2082710 - 339 WP_280628740.1 hypothetical protein -
QE207_RS12070 (QE207_12060) 2082955..2083434 - 480 WP_280628741.1 hypothetical protein -
QE207_RS12075 (QE207_12065) 2083425..2083790 - 366 WP_280628742.1 hypothetical protein -
QE207_RS12080 (QE207_12070) 2083882..2084388 - 507 WP_280628743.1 hypothetical protein -
QE207_RS12085 (QE207_12075) 2084385..2084738 - 354 WP_280628744.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15888.82 Da        Isoelectric Point: 10.8101

>T279005 WP_026821813.1 NZ_CP123498:c2080024-2079617 [Arsenophonus nasoniae]
VVLWKFNINVSWLTQLFSTGVHVGIGLLVFFSSWPPNNLVTWLIATLLIVASWVRSQKNISRCKGSIVLLNGNKIQWKKS
EWLIVKKPWFCFFGVKLTLRSWQCNKRIRLWIASDSMPEEEWRNLNQLLLQYPDI

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10612.15 Da        Isoelectric Point: 5.1149

>AT279005 WP_026821812.1 NZ_CP123498:c2080271-2080005 [Arsenophonus nasoniae]
MDINHKPRIHWACRRGMRELDIAIMPFFEYEYDSLTEDEKCLFVRLLECADPDLFNWLMNHGRPDDDGLYHMIQLIQSRN
KQRGSLEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7L3M1

Antitoxin

Source ID Structure
AlphaFold DB A0A4P7KWA0

References