Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
| Location | 493707..495174 | Replicon | chromosome |
| Accession | NZ_CP123294 | ||
| Organism | Mycoplasmopsis bovis strain 15DD0207 | ||
Toxin (Protein)
| Gene name | abiEi | Uniprot ID | Q932V7 |
| Locus tag | QEP34_RS02105 | Protein ID | WP_041309184.1 |
| Coordinates | 493707..494567 (-) | Length | 287 a.a. |
Antitoxin (Protein)
| Gene name | abiEii | Uniprot ID | Q934C3 |
| Locus tag | QEP34_RS02110 | Protein ID | WP_013456322.1 |
| Coordinates | 494560..495174 (-) | Length | 205 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QEP34_RS02080 | 489266..489616 | + | 351 | Protein_386 | variable surface lipoprotein | - |
| QEP34_RS02085 | 489884..490648 | - | 765 | WP_280135705.1 | variable surface lipoprotein | - |
| QEP34_RS02090 | 490814..491464 | - | 651 | WP_214461189.1 | variable surface lipoprotein | - |
| QEP34_RS02095 | 491652..492542 | - | 891 | WP_075271150.1 | variable surface lipoprotein | - |
| QEP34_RS02100 | 492727..493587 | - | 861 | WP_280135706.1 | variable surface lipoprotein | - |
| QEP34_RS02105 | 493707..494567 | - | 861 | WP_041309184.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| QEP34_RS02110 | 494560..495174 | - | 615 | WP_013456322.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| QEP34_RS02115 | 495357..496121 | + | 765 | WP_075270933.1 | variable surface lipoprotein | - |
| QEP34_RS02120 | 496164..496592 | - | 429 | WP_280135707.1 | hypothetical protein | - |
| QEP34_RS02125 | 496561..497805 | - | 1245 | WP_280135708.1 | IS3 family transposase | - |
| QEP34_RS02130 | 497873..498082 | - | 210 | Protein_396 | variable surface lipoprotein | - |
| QEP34_RS02135 | 498634..498816 | + | 183 | WP_235125612.1 | helix-turn-helix domain-containing protein | - |
| QEP34_RS02140 | 498921..499559 | + | 639 | WP_235125609.1 | IS30 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 287 a.a. Molecular weight: 33281.35 Da Isoelectric Point: 7.2878
>T278922 WP_041309184.1 NZ_CP123294:c494567-493707 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
Download Length: 861 bp
Antitoxin
Download Length: 205 a.a. Molecular weight: 24143.83 Da Isoelectric Point: 9.7617
>AT278922 WP_013456322.1 NZ_CP123294:c495174-494560 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
Download Length: 615 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|