Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 781264..782099 Replicon chromosome
Accession NZ_CP123266
Organism Escherichia coli strain YZLc23-1

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag N4686_RS03810 Protein ID WP_063090830.1
Coordinates 781264..781641 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag N4686_RS03815 Protein ID WP_024174331.1
Coordinates 781731..782099 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4686_RS03780 (776672) 776672..777649 + 978 WP_000633235.1 type II secretion system minor pseudopilin GspK -
N4686_RS03785 (777646) 777646..778824 + 1179 WP_000094957.1 type II secretion system protein GspL -
N4686_RS03790 (778826) 778826..779362 + 537 WP_000942795.1 GspM family type II secretion system protein YghD -
N4686_RS03795 (779643) 779643..780485 - 843 WP_042096658.1 DUF4942 domain-containing protein -
N4686_RS03800 (780570) 780570..780767 - 198 WP_000838536.1 DUF957 domain-containing protein -
N4686_RS03805 (780779) 780779..781267 - 489 WP_042096656.1 DUF5983 family protein -
N4686_RS03810 (781264) 781264..781641 - 378 WP_063090830.1 TA system toxin CbtA family protein Toxin
N4686_RS03815 (781731) 781731..782099 - 369 WP_024174331.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
N4686_RS03820 (782173) 782173..782394 - 222 WP_000692346.1 DUF987 domain-containing protein -
N4686_RS03825 (782463) 782463..782939 - 477 WP_001186725.1 RadC family protein -
N4686_RS03830 (782955) 782955..783440 - 486 WP_042096390.1 antirestriction protein -
N4686_RS03835 (783532) 783532..784350 - 819 WP_001234749.1 DUF932 domain-containing protein -
N4686_RS03840 (784441) 784441..784674 - 234 WP_001117568.1 DUF905 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(19-117)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14210.15 Da        Isoelectric Point: 6.8518

>T278847 WP_063090830.1 NZ_CP123266:c781641-781264 [Escherichia coli]
MNTLPDTHVREASRCPSPVTIWQTLLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQLGF
SACTRSQLINSIDILRARRATGLMTRDNYRMVNNITQGKHPEAQQ

Download         Length: 378 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13603.42 Da        Isoelectric Point: 6.7386

>AT278847 WP_024174331.1 NZ_CP123266:c782099-781731 [Escherichia coli]
VSDTLPGTTHPDDNHDRLWWGLPCTVTPCFGARLVQKGNRLHYLADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSG
ELNPRHQHTVTLYAKGLTCEADTLGSCGYVYLAVYPTPETKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References