Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1025279..1025920 Replicon chromosome
Accession NC_017921
Organism Burkholderia sp. KJ006

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MYA_RS18620 Protein ID WP_011881500.1
Coordinates 1025582..1025920 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MYA_RS18615 Protein ID WP_011881499.1
Coordinates 1025279..1025578 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MYA_RS18590 1020397..1021668 + 1272 WP_014724582.1 Rieske 2Fe-2S domain-containing protein -
MYA_RS18595 1021686..1022171 + 486 WP_034194948.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
MYA_RS18600 1022198..1022524 + 327 WP_011881496.1 non-heme iron oxygenase ferredoxin subunit -
MYA_RS18605 1022514..1023734 + 1221 WP_014724583.1 FAD-dependent oxidoreductase -
MYA_RS18610 1023923..1025209 + 1287 WP_014724584.1 DUF445 domain-containing protein -
MYA_RS18615 1025279..1025578 - 300 WP_011881499.1 putative addiction module antidote protein Antitoxin
MYA_RS18620 1025582..1025920 - 339 WP_011881500.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MYA_RS18625 1026277..1027917 + 1641 WP_014724587.1 acetolactate synthase large subunit -
MYA_RS18630 1027946..1029379 + 1434 WP_011881502.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-106)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12642.42 Da        Isoelectric Point: 9.4958

>T27842 WP_011881500.1 NC_017921:c1025920-1025582 [Burkholderia sp. KJ006]
MVDISSNVPYSAPTYSIRTTEVFDTWFAGLQDRVARRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRA
TIWVILLCGGDKSTQQADIRAAHAMLGRLDLE

Download         Length: 339 bp

>T27842 NC_017921:c1025920-1025582 [Burkholderia sp. KJ006]
ATGGTTGACATATCGAGTAACGTGCCTTACAGTGCTCCGACGTACAGCATCAGAACGACCGAAGTCTTCGACACATGGTT
CGCCGGTCTGCAGGATCGCGTCGCACGGCGGCGTATCCAGGCCCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACT
GGAAGTCGGCCGGCTCCCCGGTCGTCGAGATGCGTATCGACCACGGCCCCGGCTATCGCGTCTACTACGTCAGGCGCGCG
ACGATCTGGGTGATCCTGCTCTGCGGCGGCGACAAGTCGACGCAACAGGCAGACATTCGCGCCGCGCACGCAATGCTCGG
GCGGCTCGACCTGGAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10548.87 Da        Isoelectric Point: 6.0633

>AT27842 WP_011881499.1 NC_017921:c1025578-1025279 [Burkholderia sp. KJ006]
MDKISTRPWDSAAHLETDDDIADYFDACLQEGGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKARA

Download         Length: 300 bp

>AT27842 NC_017921:c1025578-1025279 [Burkholderia sp. KJ006]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGCCCACCTCGAAACCGACGACGACATCGCCGACTATTTCGACGC
ATGTCTGCAGGAAGGCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGCGCGCGCGGCATGTCGC
AGGTCGCACGCGACGCCGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTCAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAAGCGCGCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References