Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | hok-ralA/- |
| Location | 3826703..3827124 | Replicon | chromosome |
| Accession | NZ_CP123008 | ||
| Organism | Escherichia coli strain NWU_4 | ||
Toxin (Protein)
| Gene name | hok | Uniprot ID | - |
| Locus tag | QEN27_RS18400 | Protein ID | WP_096937776.1 |
| Coordinates | 3826999..3827124 (+) | Length | 42 a.a. |
Antitoxin (RNA)
| Gene name | ralA | ||
| Locus tag | - | ||
| Coordinates | 3826703..3826901 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QEN27_RS18365 (3821806) | 3821806..3822315 | - | 510 | WP_071600123.1 | hypothetical protein | - |
| QEN27_RS18370 (3822633) | 3822633..3823172 | + | 540 | WP_000290801.1 | single-stranded DNA-binding protein | - |
| QEN27_RS18375 (3823229) | 3823229..3823462 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| QEN27_RS18380 (3823528) | 3823528..3825486 | + | 1959 | WP_000117173.1 | ParB/RepB/Spo0J family partition protein | - |
| QEN27_RS18385 (3825541) | 3825541..3825975 | + | 435 | WP_000845928.1 | conjugation system SOS inhibitor PsiB | - |
| QEN27_RS18390 (3825972) | 3825972..3826734 | + | 763 | Protein_3617 | plasmid SOS inhibition protein A | - |
| - (3826703) | 3826703..3826901 | + | 199 | NuclAT_1 | - | Antitoxin |
| - (3826703) | 3826703..3826901 | + | 199 | NuclAT_1 | - | Antitoxin |
| - (3826703) | 3826703..3826901 | + | 199 | NuclAT_1 | - | Antitoxin |
| - (3826703) | 3826703..3826901 | + | 199 | NuclAT_1 | - | Antitoxin |
| QEN27_RS18395 (3826908) | 3826908..3827057 | + | 150 | Protein_3618 | DUF5431 family protein | - |
| QEN27_RS18400 (3826999) | 3826999..3827124 | + | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin |
| QEN27_RS18405 (3827425) | 3827425..3827721 | - | 297 | Protein_3620 | hypothetical protein | - |
| QEN27_RS18410 (3827791) | 3827791..3827997 | + | 207 | WP_000547965.1 | hypothetical protein | - |
| QEN27_RS18415 (3828022) | 3828022..3828309 | + | 288 | WP_000107542.1 | hypothetical protein | - |
| QEN27_RS18420 (3828428) | 3828428..3829249 | + | 822 | WP_001234417.1 | DUF932 domain-containing protein | - |
| QEN27_RS18425 (3829545) | 3829545..3830147 | - | 603 | WP_000243701.1 | transglycosylase SLT domain-containing protein | - |
| QEN27_RS18430 (3830469) | 3830469..3830852 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| QEN27_RS18435 (3831042) | 3831042..3831728 | + | 687 | WP_000332492.1 | PAS domain-containing protein | - |
| QEN27_RS18440 (3831822) | 3831822..3832049 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 42 a.a. Molecular weight: 4806.72 Da Isoelectric Point: 8.4890
>T278374 WP_096937776.1 NZ_CP123008:3826999-3827124 [Escherichia coli]
VLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK
VLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK
Download Length: 126 bp
Antitoxin
Download Length: 199 bp
>AT278374 NZ_CP123008:3826703-3826901 [Escherichia coli]
TCACACAGATTACCCGTAAACAGCCTGAATGAGCGGGTTATTTTCAGGAAAAGTGAGTGTGGTCAGCGTGCAGGGATATG
GGCTATGATGTGCCCGGCGCTTGAGGCTTTCTGCCTCATGACGTGAAGGTGGTTTGTTGCCGTGTTGTGTGGCAGAAGGA
CAAAAGCCCCGTAGTTAATTTTTCATTAACCCACGAGGC
TCACACAGATTACCCGTAAACAGCCTGAATGAGCGGGTTATTTTCAGGAAAAGTGAGTGTGGTCAGCGTGCAGGGATATG
GGCTATGATGTGCCCGGCGCTTGAGGCTTTCTGCCTCATGACGTGAAGGTGGTTTGTTGCCGTGTTGTGTGGCAGAAGGA
CAAAAGCCCCGTAGTTAATTTTTCATTAACCCACGAGGC
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
