Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2182773..2183044 Replicon chromosome
Accession NZ_CP122652
Organism Escherichia coli strain ETEC4075

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2182903..2183006 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2182773..2183044 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDW61_RS10635 2179328..2179990 - 663 WP_000944256.1 exodeoxyribonuclease X -
QDW61_RS10640 2180014..2180670 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
QDW61_RS10645 2180772..2181002 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QDW61_RS10650 2181141..2181515 + 375 WP_000204705.1 CopC domain-containing protein YobA -
QDW61_RS10655 2181519..2182391 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
QDW61_RS10660 2182404..2182745 + 342 WP_000976472.1 YebY family protein -
- 2182773..2183044 - 272 - - Antitoxin
- 2182903..2183006 + 104 - - Toxin
QDW61_RS10665 2183141..2183797 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
QDW61_RS10670 2183798..2183989 - 192 WP_001296140.1 YebW family protein -
QDW61_RS10675 2184094..2184330 - 237 WP_001295499.1 YebV family protein -
QDW61_RS10680 2184448..2185887 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2175463..2185893 10430
- inside Prophage - - 2173600..2198884 25284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T277528 NZ_CP122652:2182903-2183006 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT277528 NZ_CP122652:c2183044-2182773 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References