Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2226856..2227127 Replicon chromosome
Accession NZ_CP122648
Organism Escherichia coli strain ETEC4077

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2226986..2227089 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2226856..2227127 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDY56_RS10955 2223411..2224073 - 663 WP_000944256.1 exodeoxyribonuclease X -
QDY56_RS10960 2224097..2224753 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
QDY56_RS10965 2224855..2225085 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QDY56_RS10970 2225224..2225598 + 375 WP_000204705.1 CopC domain-containing protein YobA -
QDY56_RS10975 2225602..2226474 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
QDY56_RS10980 2226487..2226828 + 342 WP_000976472.1 YebY family protein -
- 2226856..2227127 - 272 - - Antitoxin
- 2226986..2227089 + 104 - - Toxin
QDY56_RS10985 2227224..2227880 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
QDY56_RS10990 2227881..2228072 - 192 WP_001296140.1 YebW family protein -
QDY56_RS10995 2228177..2228413 - 237 WP_001295499.1 YebV family protein -
QDY56_RS11000 2228531..2229970 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2205013..2242967 37954
- inside Prophage - - 2203073..2242967 39894


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T277504 NZ_CP122648:2226986-2227089 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT277504 NZ_CP122648:c2227127-2226856 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References