Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 367422..367953 Replicon chromosome
Accession NC_017845
Organism Pectobacterium sp. SCC3193

Toxin (Protein)


Gene name stbE Uniprot ID A0A1V2R9S3
Locus tag W5S_RS01670 Protein ID WP_012822123.1
Coordinates 367666..367953 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A0H3HYL0
Locus tag W5S_RS01665 Protein ID WP_012822122.1
Coordinates 367422..367676 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
W5S_RS01650 364035..364922 + 888 WP_014698523.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
W5S_RS24485 366341..366625 + 285 Protein_320 hypothetical protein -
W5S_RS01660 366846..367142 + 297 WP_052301439.1 hypothetical protein -
W5S_RS01665 367422..367676 + 255 WP_012822122.1 plasmid stabilization protein Antitoxin
W5S_RS01670 367666..367953 + 288 WP_012822123.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
W5S_RS01675 368132..368920 + 789 WP_014698525.1 4,5-DOPA dioxygenase extradiol -
W5S_RS01680 369008..370168 - 1161 WP_014698526.1 glutathionylspermidine synthase family protein -
W5S_RS01685 370180..370848 - 669 WP_012822126.1 DUF1190 family protein -
W5S_RS01690 371132..372523 - 1392 WP_014698527.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10997.94 Da        Isoelectric Point: 10.7694

>T27726 WP_012822123.1 NC_017845:367666-367953 [Pectobacterium parmentieri]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQVYSDTKGRSA

Download         Length: 288 bp

>T27726 NC_017845:367666-367953 [Pectobacterium parmentieri]
ATGACCTATAAGTTAAAATTTGTGCCTTCTGCAATGAAGGAATGGAAAAAATTAGGGCATCCTGTCAGGGAACAATTCAA
AAAAAAGCTAGTTGAGCGTTTAGAAAATCCTCGCGTTCCTTCAGCCCAGCTTCATGGTCGTAAAGACCAGTATAAAATTA
AACTGAAGTCTGCTGGTTACAGGTTGGTGTATTTGGTTCAGGATGAGACCATTACGGTGATGGTCATGGGGGTTGGAAAG
CGCGAAGGTAGTCAGGTTTATTCTGATACTAAAGGTCGCTCTGCTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9237.47 Da        Isoelectric Point: 3.9490

>AT27726 WP_012822122.1 NC_017845:367422-367676 [Pectobacterium parmentieri]
MAFNILTNTAASITELKRDPMGTVRSAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDERMSEIADAKEIS
LDDL

Download         Length: 255 bp

>AT27726 NC_017845:367422-367676 [Pectobacterium parmentieri]
ATGGCTTTCAATATTCTAACTAACACAGCAGCCAGTATTACTGAGTTGAAACGTGACCCAATGGGGACGGTGCGATCTGC
TGAAGGTGAAACTATCGCTATACTGAACCGCAATGAGCCTGCGTTCTATTGCGTGCCTCCTGCTGTGTTCGCTTACTTGA
TGGAACTCGCTGAAGATGCAGAATTGGGGCGTACCGTTGATGAGCGGATGTCAGAGATAGCTGATGCGAAAGAGATTTCG
CTCGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1V2R9S3

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3HYL0

References