Detailed information of TA system TA276954

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3611145..3611549
• Replicon: chromosome
• Accession: NZ_CP122457
• Organism: Salmonella enterica subsp. enterica strain TZ282

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: QCX26_RS17445
• Protein ID: WP_080171486.1
• Coordinates: 3611292..3611549 (+)
• Length: 86 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3611145..3611467 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QCX26_RS17415	3606399..3606911	-	513	WP_197399601.1	pilus assembly protein	-
QCX26_RS17420	3607661..3608365	-	705	Protein_3406	integrase core domain-containing protein	-
QCX26_RS17425	3608418..3608732	+	315	WP_023892102.1	SymE family type I addiction module toxin	-
QCX26_RS17430	3608799..3609077	-	279	WP_080222338.1	hypothetical protein	-
QCX26_RS17435	3609395..3609862	-	468	WP_283880265.1	sugar tyrosine-protein kinase	-
QCX26_RS17440	3610734..3610967	-	234	WP_197399602.1	hypothetical protein	-
-	3611145..3611467	-	323	-	-	Antitoxin
QCX26_RS17445	3611292..3611549	+	258	WP_080171486.1	SymE family type I addiction module toxin	Toxin
QCX26_RS17450	3611608..3611916	-	309	WP_001080453.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3589188..3643231	54043

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (14-56)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 9486.88 Da
• Isoelectric Point: 7.1321

>T276954 WP_080171486.1 NZ_CP122457:3611292-3611549 [Salmonella enterica subsp. enterica]
MNASGVSVRHINSETYITTCYSQIPSLHLKGDWLEEAGFKTGRGVTVKISQGCIVLMADSNEEQKLREQLYKAEQVVKGM
RDVIV

Nucleotide

• Length: 258 bp

Antitoxin

Nucleotide

• Length: 323 bp

>AT276954 NZ_CP122457:c3611467-3611145 [Salmonella enterica subsp. enterica]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGGTGCAGGCTGGGGATTTGTGAGTAACAGGTGGTTATATAGGTTTCGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGTGAGTATGGGCGCGACATCCTGGCACTGTGCCCCCCTCTCCCCGGCCAGTGATGAGCAACCGGCTGCCGGGGCCGTAT
TTT

Structures

Antitoxin