Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 132739..133265 Replicon plasmid pPAG03
Accession NZ_CP122322
Organism Pantoea agglomerans pv. gypsophilae strain 824-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A7P62_RS22725 Protein ID WP_064689878.1
Coordinates 132978..133265 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8X8DPB7
Locus tag A7P62_RS22720 Protein ID WP_010257033.1
Coordinates 132739..132978 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7P62_RS22705 (A7P62_22705) 128714..129235 + 522 WP_231113895.1 DUF2268 domain-containing putative Zn-dependent protease -
A7P62_RS22710 (A7P62_22710) 129285..130301 - 1017 WP_010257039.1 NAD(P)-dependent alcohol dehydrogenase -
A7P62_RS22715 (A7P62_22715) 130406..132379 - 1974 WP_064689879.1 methyl-accepting chemotaxis protein -
A7P62_RS22720 (A7P62_22720) 132739..132978 + 240 WP_010257033.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
A7P62_RS22725 (A7P62_22725) 132978..133265 + 288 WP_064689878.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A7P62_RS22730 (A7P62_22730) 133310..133606 - 297 WP_033770131.1 hypothetical protein -
A7P62_RS22735 (A7P62_22735) 133808..133984 + 177 WP_010257023.1 KGG domain-containing protein -
A7P62_RS22740 (A7P62_22740) 134048..134944 - 897 WP_010257019.1 LysR family transcriptional regulator -
A7P62_RS22745 (A7P62_22745) 135147..136271 + 1125 WP_081276205.1 MFS transporter -
A7P62_RS22750 (A7P62_22750) 136340..137365 + 1026 WP_010671942.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..143524 143524


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-77)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11119.03 Da        Isoelectric Point: 10.3173

>T276796 WP_064689878.1 NZ_CP122322:132978-133265 [Pantoea agglomerans pv. gypsophilae]
MTWQLEFDQRALKEWRKLGPTVREQLKKKLAECLESPRIEANKLSGMPDCYKIKLKSSGYRLVYQVIDDRVVVFVVAVVK
RERSEVYSAASRRLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9002.33 Da        Isoelectric Point: 4.3410

>AT276796 WP_010257033.1 NZ_CP122322:132739-132978 [Pantoea agglomerans pv. gypsophilae]
MGTINIRIDDDLKTRSYAALEKMGVTPSDALRLMLEYIADNERLPFKQTLLSDEDAALVDIVKERLRNPEPVRVTLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References