Detailed information of TA system TA027668

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 6739..7364
• Replicon: plasmid pSLT_SL1344
• Accession: NC_017720
• Organism: Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: SL1344_RS23660
• Protein ID: WP_000911322.1
• Coordinates: 6966..7364 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: SL1344_RS23655
• Protein ID: WP_000450265.1
• Coordinates: 6739..6966 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SL1344_RS23655	6739..6966	+	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin
SL1344_RS23660	6966..7364	+	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
SL1344_RS23665	7373..9535	-	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
SL1344_RS23670	9912..10643	-	732	WP_000782438.1	complement resistance protein TraT	-
SL1344_RS23675	10679..11173	-	495	WP_010999946.1	entry exclusion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93842	93842

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-120)

Antitoxin

• Ribbon-helix-helix protein, CopG (4-39)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 17065.17 Da
• Isoelectric Point: 12.9205

>T27668 WP_000911322.1 NC_017720:6966-7364 [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344]
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KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 399 bp

>T27668 NC_017720:6966-7364 [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
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AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 9759.25 Da
• Isoelectric Point: 12.6750

>AT27668 WP_000450265.1 NC_017720:6739-6966 [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 228 bp

>AT27668 NC_017720:6739-6966 [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA