Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3335362..3336015 Replicon chromosome
Accession NZ_CP121598
Organism Acinetobacter baumannii strain JAB77

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS78_RS16075 Protein ID WP_000607077.1
Coordinates 3335362..3335751 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS78_RS16080 Protein ID WP_001288210.1
Coordinates 3335758..3336015 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS78_RS16060 (MTS78_16060) 3330480..3332675 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
MTS78_RS16065 (MTS78_16065) 3332863..3333429 - 567 WP_000651538.1 rhombosortase -
MTS78_RS16070 (MTS78_16070) 3333507..3334592 - 1086 WP_000049106.1 hypothetical protein -
MTS78_RS16075 (MTS78_16075) 3335362..3335751 - 390 WP_000607077.1 membrane protein Toxin
MTS78_RS16080 (MTS78_16080) 3335758..3336015 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS78_RS16085 (MTS78_16085) 3336203..3337375 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS78_RS16090 (MTS78_16090) 3337424..3338914 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS78_RS16095 (MTS78_16095) 3339096..3339473 - 378 WP_064894046.1 50S ribosomal protein L17 -
MTS78_RS16100 (MTS78_16100) 3339492..3340499 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276444 WP_000607077.1 NZ_CP121598:c3335751-3335362 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276444 WP_001288210.1 NZ_CP121598:c3336015-3335758 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References