Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1204937..1205772 Replicon chromosome
Accession NZ_CP121356
Organism Escherichia coli strain rl0044

Toxin (Protein)


Gene name yeeV Uniprot ID A0A8S7S8K0
Locus tag P9060_RS05915 Protein ID WP_000854723.1
Coordinates 1204937..1205314 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID A0A8S7S6L8
Locus tag P9060_RS05920 Protein ID WP_001285573.1
Coordinates 1205404..1205772 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9060_RS05890 (1200315) 1200315..1202567 - 2253 Protein_1153 alpha-amylase family glycosyl hydrolase -
P9060_RS05900 (1203301) 1203301..1204146 - 846 WP_001290254.1 DUF4942 domain-containing protein -
P9060_RS05905 (1204243) 1204243..1204440 - 198 WP_000772035.1 DUF957 domain-containing protein -
P9060_RS05910 (1204452) 1204452..1204940 - 489 WP_000761669.1 DUF5983 family protein -
P9060_RS05915 (1204937) 1204937..1205314 - 378 WP_000854723.1 TA system toxin CbtA family protein Toxin
P9060_RS05920 (1205404) 1205404..1205772 - 369 WP_001285573.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
P9060_RS05925 (1205852) 1205852..1206073 - 222 WP_000692176.1 DUF987 domain-containing protein -
P9060_RS05930 (1206160) 1206160..1206636 - 477 WP_001360063.1 RadC family protein -
P9060_RS05935 (1206652) 1206652..1207146 - 495 WP_032167345.1 antirestriction protein -
P9060_RS05940 (1207238) 1207238..1208056 - 819 WP_032167344.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14145.23 Da        Isoelectric Point: 8.2904

>T276297 WP_000854723.1 NZ_CP121356:c1205314-1204937 [Escherichia coli]
MKTLPDTHVREASRCPSPVTIWQILLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
STCTRSQLINSIDILRTRRATGLMARDNYRTVNNIILGKHPGAKQ

Download         Length: 378 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13585.33 Da        Isoelectric Point: 6.3159

>AT276297 WP_001285573.1 NZ_CP121356:c1205772-1205404 [Escherichia coli]
VSDTLPGTTHPDDNNDRPWWGLPCSVTPCFGARLVQEGNRLHYLADRAGIRGRFSDADSYHLDQAFPLLMKQLELMLTSG
ELSPRHQHTVTLYAKGLTCEADTLGSCGYVYMAVYPTPETKK

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References