Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 5867439..5868256 Replicon chromosome
Accession NZ_CP120956
Organism Delftia tsuruhatensis strain Ery-6A

Toxin (Protein)


Gene name yhaV Uniprot ID A0A1H3PAE7
Locus tag PYR84_RS26590 Protein ID WP_074922422.1
Coordinates 5867765..5868256 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag PYR84_RS26585 Protein ID WP_160854329.1
Coordinates 5867439..5867768 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYR84_RS26565 (PYR84_26565) 5862989..5863822 - 834 WP_074922418.1 helix-turn-helix transcriptional regulator -
PYR84_RS26570 (PYR84_26570) 5863893..5864555 + 663 WP_277849008.1 pyridoxamine 5'-phosphate oxidase family protein -
PYR84_RS26575 (PYR84_26575) 5864583..5864978 + 396 WP_277849009.1 hypothetical protein -
PYR84_RS26580 (PYR84_26580) 5865102..5867342 + 2241 WP_277849010.1 TonB-dependent receptor -
PYR84_RS26585 (PYR84_26585) 5867439..5867768 + 330 WP_160854329.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
PYR84_RS26590 (PYR84_26590) 5867765..5868256 + 492 WP_074922422.1 type II toxin-antitoxin system YhaV family toxin Toxin
PYR84_RS26595 (PYR84_26595) 5868271..5868783 - 513 WP_016448386.1 MgtC/SapB family protein -
PYR84_RS26600 (PYR84_26600) 5868898..5870325 - 1428 WP_277849011.1 chloride channel protein -
PYR84_RS26605 (PYR84_26605) 5870600..5870929 - 330 WP_013800515.1 DHCW motif cupin fold protein -
PYR84_RS26610 (PYR84_26610) 5870993..5871811 - 819 WP_277849012.1 precorrin-6A synthase (deacetylating) -
PYR84_RS26615 (PYR84_26615) 5871808..5872674 - 867 WP_277849013.1 precorrin-4 C(11)-methyltransferase -
PYR84_RS26620 (PYR84_26620) 5872671..5873156 - 486 WP_016452700.1 cobalamin biosynthesis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18772.38 Da        Isoelectric Point: 10.2215

>T275482 WP_074922422.1 NZ_CP120956:5867765-5868256 [Delftia tsuruhatensis]
MSAVPPAPLRIHGWTVFMHPLFLAQLQALSHEVEGLKTKDPGGYTRKNATKRLAAIRKLAFDVIPQDPTRPDYRQGHTLG
EEHKHWFRARFFQQYRLFFRFHAPSKIIVFAWVNDEDTKRAYEGSDDAYRVFRKMLANGHPPGDWDSLLAQAKSPPPDSQ
PHA

Download         Length: 492 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12092.56 Da        Isoelectric Point: 4.1858

>AT275482 WP_160854329.1 NZ_CP120956:5867439-5867768 [Delftia tsuruhatensis]
MFSTLEAESTLTDRYQTTIPEAVRRALHLSKRDRIHYTILPGGEVVLSRADSTEDADPVLGQFLGFLAQDMAAHPERLQT
MDARLAQQIQALTEGIEVDLDAPLLADDE

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H3PAE7

Antitoxin

Source ID Structure

References