Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2459470..2459738 Replicon chromosome
Accession NZ_CP120567
Organism Escherichia coli strain A0 34/86

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2459598..2459700 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2459470..2459738 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5707_RS11730 2456022..2456684 - 663 WP_000944256.1 exodeoxyribonuclease X -
P5707_RS11735 2456708..2457364 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
P5707_RS11740 2457467..2457697 - 231 WP_000916763.1 DNA polymerase III subunit theta -
P5707_RS11745 2457836..2458210 + 375 WP_000168747.1 CopC domain-containing protein YobA -
P5707_RS11750 2458214..2459086 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
P5707_RS11755 2459099..2459440 + 342 WP_000984819.1 YebY family protein -
- 2459470..2459738 - 269 - - Antitoxin
- 2459598..2459700 + 103 - - Toxin
P5707_RS11760 2459835..2460491 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
P5707_RS11765 2460492..2460683 - 192 WP_001317886.1 YebW family protein -
P5707_RS11770 2460788..2461024 - 237 WP_001295499.1 YebV family protein -
P5707_RS11775 2461142..2462581 - 1440 WP_012601553.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275188 NZ_CP120567:2459598-2459700 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT275188 NZ_CP120567:c2459738-2459470 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References