Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1185937..1186477 Replicon chromosome
Accession NZ_CP119766
Organism Flavobacterium sp. CJ75

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag P2W65_RS05395 Protein ID WP_289664003.1
Coordinates 1186181..1186477 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag P2W65_RS05390 Protein ID WP_289664001.1
Coordinates 1185937..1186191 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2W65_RS05370 1181947..1183344 - 1398 WP_289663992.1 glycosyl hydrolase family 8 -
P2W65_RS05375 1183446..1183625 - 180 WP_008465789.1 twin-arginine translocase TatA/TatE family subunit -
P2W65_RS05380 1183840..1184343 + 504 WP_289663997.1 peptidase -
P2W65_RS05385 1184354..1185838 + 1485 WP_289663999.1 GH3 auxin-responsive promoter family protein -
P2W65_RS05390 1185937..1186191 + 255 WP_289664001.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
P2W65_RS05395 1186181..1186477 + 297 WP_289664003.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P2W65_RS05400 1186544..1188223 + 1680 WP_289664004.1 hypothetical protein -
P2W65_RS05405 1188233..1189219 + 987 WP_289664006.1 hypothetical protein -
P2W65_RS05410 1189227..1190528 + 1302 WP_289664007.1 MATE family efflux transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-81)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11930.87 Da        Isoelectric Point: 8.0401

>T274442 WP_289664003.1 NZ_CP119766:1186181-1186477 [Flavobacterium sp. CJ75]
MNYKISIEASYDLEKIWLYTFDTWSAEQADRYLKLILDEIEYLCLKPNSGKDFSHIRKGYFRTKVKSHLIFYKINIKQNE
IEIIRVLHQMMDIENHLK

Download         Length: 297 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9785.13 Da        Isoelectric Point: 7.2048

>AT274442 WP_289664001.1 NZ_CP119766:1185937-1186191 [Flavobacterium sp. CJ75]
MAKNTSILLGDYFDNFINSQVKTGRFTSASEVIRAALRMFEEEQTKSEELIKELKKGEKSGFVKDFDRESFIKNLHEKHI
KNEL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References