Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1303033..1303653 Replicon chromosome
Accession NZ_CP119754
Organism Superficieibacter sp. HKU1

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag P0H77_RS06260 Protein ID WP_176917457.1
Coordinates 1303033..1303251 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag P0H77_RS06265 Protein ID WP_276164054.1
Coordinates 1303279..1303653 (-) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0H77_RS06230 (P0H77_06235) 1299109..1299369 + 261 WP_276164049.1 type B 50S ribosomal protein L31 -
P0H77_RS06235 (P0H77_06240) 1299373..1299513 + 141 WP_003859006.1 type B 50S ribosomal protein L36 -
P0H77_RS06240 (P0H77_06245) 1299510..1300211 - 702 WP_276165059.1 GNAT family protein -
P0H77_RS06245 (P0H77_06250) 1300317..1301774 + 1458 WP_276164051.1 PLP-dependent aminotransferase family protein -
P0H77_RS06250 (P0H77_06255) 1301734..1302213 - 480 WP_276164052.1 YlaC family protein -
P0H77_RS06255 (P0H77_06260) 1302314..1302871 - 558 WP_276164053.1 maltose O-acetyltransferase -
P0H77_RS06260 (P0H77_06265) 1303033..1303251 - 219 WP_176917457.1 HHA domain-containing protein Toxin
P0H77_RS06265 (P0H77_06270) 1303279..1303653 - 375 WP_276164054.1 Hha toxicity modulator TomB Antitoxin
P0H77_RS06270 (P0H77_06275) 1304066..1307212 - 3147 WP_276164055.1 multidrug efflux RND transporter permease subunit AcrB -
P0H77_RS06275 (P0H77_06280) 1307235..1308428 - 1194 WP_276164056.1 multidrug efflux RND transporter periplasmic adaptor subunit AcrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-115)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8640.01 Da        Isoelectric Point: 7.9906

>T274428 WP_176917457.1 NZ_CP119754:c1303251-1303033 [Superficieibacter sp. HKU1]
MTDKALTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELVVFYSAADHRLAELTMNKLYDKIPPSVWQFIR

Download         Length: 219 bp

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14464.18 Da        Isoelectric Point: 4.6598

>AT274428 WP_276164054.1 NZ_CP119754:c1303653-1303279 [Superficieibacter sp. HKU1]
MDEYSPKRHDIAQLKFLCENLYHDCIANLDESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYNEDNNLVMQIDEYL
DDTFMLFSNYGISTQDLQKWRKSGNNLFHCFVNVSQANPARLSC

Download         Length: 375 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References