Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 324116..324879 Replicon chromosome
Accession NZ_CP119754
Organism Superficieibacter sp. HKU1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag P0H77_RS01545 Protein ID WP_276161552.1
Coordinates 324403..324879 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag P0H77_RS01540 Protein ID WP_276161546.1
Coordinates 324116..324412 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0H77_RS01515 (P0H77_01515) 320475..321668 + 1194 WP_276161514.1 NAD(P)/FAD-dependent oxidoreductase -
P0H77_RS01520 (P0H77_01520) 321907..322239 + 333 WP_276161519.1 DUF1971 domain-containing protein -
P0H77_RS01525 (P0H77_01525) 322250..322588 + 339 WP_276161523.1 DUF1869 domain-containing protein -
P0H77_RS01530 (P0H77_01530) 322612..322968 + 357 WP_276161529.1 DUF1971 domain-containing protein -
P0H77_RS01535 (P0H77_01535) 323140..323934 - 795 WP_276161537.1 SDR family oxidoreductase -
P0H77_RS01540 (P0H77_01540) 324116..324412 + 297 WP_276161546.1 DUF1778 domain-containing protein Antitoxin
P0H77_RS01545 (P0H77_01545) 324403..324879 + 477 WP_276161552.1 GNAT family N-acetyltransferase Toxin
P0H77_RS01550 (P0H77_01550) 324886..325284 - 399 WP_276161559.1 nickel-responsive transcriptional regulator NikR -
P0H77_RS01555 (P0H77_01555) 325297..326073 - 777 WP_276161564.1 nickel import ATP-binding protein NikE -
P0H77_RS01560 (P0H77_01560) 326070..326834 - 765 WP_276161567.1 nickel import ATP-binding protein NikD -
P0H77_RS01565 (P0H77_01565) 326834..327667 - 834 WP_276161571.1 nickel ABC transporter permease subunit NikC -
P0H77_RS01570 (P0H77_01570) 327664..328608 - 945 WP_276161578.1 nickel ABC transporter permease subunit NikB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-147)

Antitoxin

Vibrio phage ICP1, Orf50

(17-91)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 17908.72 Da        Isoelectric Point: 8.7215

>T274425 WP_276161552.1 NZ_CP119754:324403-324879 [Superficieibacter sp. HKU1]
MEVTTPKILTDTHVMTDFCCGNSVLDDWLMRRALKKQALNASRTFVTCESGTRNVVGYYSLASGSVTHHAVPRGLRQNMP
EPIPVILLGRLAVDQRYQGQDMGKWLLNDVVNRVINVAEQIGVKAMMVHAINEDARRFYKHFGFVQSVIAEDTLFWRL

Download         Length: 477 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11300.82 Da        Isoelectric Point: 4.8660

>AT274425 WP_276161546.1 NZ_CP119754:324116-324412 [Superficieibacter sp. HKU1]
MPASTAKVSKKFNRDNQINLRASDAERAIIDYAASLLNKSRTDFILELAYNEAQNIILDQRLFVLDADKYQAFVEQLEAP
LENVEGRNRLMDVKPEWK

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References