Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 123878..124527 Replicon chromosome
Accession NZ_CP119754
Organism Superficieibacter sp. HKU1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag P0H77_RS00615 Protein ID WP_276160945.1
Coordinates 124186..124527 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag P0H77_RS00610 Protein ID WP_276160944.1
Coordinates 123878..124189 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0H77_RS00590 (P0H77_00590) 119460..120971 - 1512 WP_276160940.1 glycerol kinase GlpK -
P0H77_RS00595 (P0H77_00595) 120994..121839 - 846 WP_276160941.1 MIP/aquaporin family protein -
P0H77_RS00600 (P0H77_00600) 122273..122512 + 240 WP_103676369.1 septal ring assembly protein ZapB -
P0H77_RS00605 (P0H77_00605) 122656..123645 + 990 WP_276160942.1 sulfate ABC transporter substrate-binding protein -
P0H77_RS00610 (P0H77_00610) 123878..124189 - 312 WP_276160944.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
P0H77_RS00615 (P0H77_00615) 124186..124527 - 342 WP_276160945.1 toxin Toxin
P0H77_RS00620 (P0H77_00620) 124776..125555 + 780 WP_276160947.1 CDP-diacylglycerol diphosphatase -
P0H77_RS00625 (P0H77_00625) 125578..127170 - 1593 WP_276160949.1 autoinducer-2 kinase -
P0H77_RS00630 (P0H77_00630) 127256..128221 - 966 WP_276160951.1 transcriptional regulator LsrR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(44-87)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13502.43 Da        Isoelectric Point: 9.7093

>T274424 WP_276160945.1 NZ_CP119754:c124527-124186 [Superficieibacter sp. HKU1]
MDALFIELPPFERHRAEYFSDEEFRAFQQFLLKNPTCGDVIPDAGGLRKVRFLDSRRNKGKRGGIRVIYYWYLEKSHFLL
FTLYDKDQLDDLTTQQRNVLRQLLEQAKQRGKS

Download         Length: 342 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11797.52 Da        Isoelectric Point: 8.5259

>AT274424 WP_276160944.1 NZ_CP119754:c124189-123878 [Superficieibacter sp. HKU1]
MTQRNIFSELTEGFQAWEEYDAGKITLRTHRVNTETPAISPDDLVKVREKLNLSQAVFAQYLHAGLRTYQNWEQGLARPN
KQAVLLIRMIEKSPSVLSQLAIL

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References