Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2510980..2511164 Replicon chromosome
Accession NZ_CP119338
Organism Staphylococcus aureus strain N09HSA11

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag P1A14_RS12520 Protein ID WP_000482647.1
Coordinates 2511057..2511164 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2510980..2511040 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1A14_RS12505 (P1A14_12505) 2506510..2506677 - 168 WP_001790576.1 hypothetical protein -
P1A14_RS12510 (P1A14_12510) 2506908..2508641 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
P1A14_RS12515 (P1A14_12515) 2508666..2510429 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2510980..2511040 + 61 - - Antitoxin
P1A14_RS12520 (P1A14_12520) 2511057..2511164 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
P1A14_RS12525 (P1A14_12525) 2511298..2511684 - 387 WP_000779360.1 flippase GtxA -
P1A14_RS12530 (P1A14_12530) 2511942..2513084 + 1143 WP_001176863.1 glycerate kinase -
P1A14_RS12535 (P1A14_12535) 2513144..2513803 + 660 WP_000831298.1 membrane protein -
P1A14_RS12540 (P1A14_12540) 2513985..2515196 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
P1A14_RS12545 (P1A14_12545) 2515319..2515792 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T273987 WP_000482647.1 NZ_CP119338:c2511164-2511057 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT273987 NZ_CP119338:2510980-2511040 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References