Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1894808..1895076 Replicon chromosome
Accession NC_017634
Organism Escherichia coli O83:H1 str. NRG 857C

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1894846..1894948 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1894808..1895076 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRG857_RS09390 1891965..1893404 + 1440 WP_024190479.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NRG857_RS09395 1893522..1893758 + 237 WP_001295499.1 DUF1480 family protein -
NRG857_RS09400 1893863..1894054 + 192 WP_001317886.1 YebW family protein -
NRG857_RS09405 1894055..1894711 - 657 WP_000812746.1 protein-serine/threonine phosphatase -
- 1894808..1895076 + 269 - - Antitoxin
- 1894846..1894948 - 103 - - Toxin
NRG857_RS09410 1895106..1895447 - 342 WP_000976472.1 YebY family protein -
NRG857_RS09415 1895460..1896332 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
NRG857_RS09420 1896336..1896710 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NRG857_RS09425 1896849..1897079 + 231 WP_000916763.1 DNA polymerase III subunit theta -
NRG857_RS09430 1897181..1897837 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
NRG857_RS09435 1897860..1898522 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T27336 NC_017634:c1894948-1894846 [Escherichia coli O83:H1 str. NRG 857C]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT27336 NC_017634:1894808-1895076 [Escherichia coli O83:H1 str. NRG 857C]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References