Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 3642979..3643678 Replicon chromosome
Accession NZ_CP118629
Organism Pantoea dispersa strain VWJL.P1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag PWF83_RS17015 Protein ID WP_072208527.1
Coordinates 3643502..3643678 (-) Length 59 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag PWF83_RS17010 Protein ID WP_058757543.1
Coordinates 3642979..3643383 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWF83_RS16995 (PWF83_17005) 3640148..3640387 + 240 WP_211724902.1 hypothetical protein -
PWF83_RS17000 (PWF83_17010) 3640482..3641921 - 1440 WP_058780881.1 PTS N-acetylmuramic acid transporter subunit IIBC -
PWF83_RS17005 (PWF83_17015) 3641921..3642832 - 912 WP_058757601.1 N-acetylmuramic acid 6-phosphate etherase -
PWF83_RS17010 (PWF83_17020) 3642979..3643383 - 405 WP_058757543.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
PWF83_RS17015 (PWF83_17025) 3643502..3643678 - 177 WP_072208527.1 type II toxin-antitoxin system HicA family toxin Toxin
PWF83_RS17020 (PWF83_17030) 3643854..3645155 - 1302 WP_021507820.1 glutamate/aspartate:proton symporter GltP -
PWF83_RS17025 (PWF83_17035) 3645736..3647691 + 1956 WP_275026688.1 acetate--CoA ligase -
PWF83_RS17030 (PWF83_17040) 3647865..3648194 + 330 WP_021313201.1 DUF485 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-55)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-127)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6824.11 Da        Isoelectric Point: 10.6691

>T273322 WP_072208527.1 NZ_CP118629:c3643678-3643502 [Pantoea dispersa]
MSSRELIRMLLERGWILDRVKGSHHVFVRADKPYHISLPHPEKDLATGTLRKLLKMMD

Download         Length: 177 bp

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 14655.39 Da        Isoelectric Point: 4.9322

>AT273322 WP_058757543.1 NZ_CP118629:c3643383-3642979 [Pantoea dispersa]
MRFPVYLHKTENGSWSGFVPDVQGCFFAGNTVDEALSDAFGAIDAHVESLADAGKAIPKAASVETHINDEECQGGYWAFV
EIDLSRYEGKAVKLNITLPQNLLTKIDSHVEAHREYGSRSGFLAALARRELANI

Download         Length: 405 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References