Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2761023..2761166 Replicon chromosome
Accession NZ_CP118536
Organism Salmonella enterica subsp. enterica serovar Typhi strain S7

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2761025..2761127 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2761023..2761166 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWA19_RS13810 (PWA19_13810) 2758301..2759431 + 1131 WP_000529513.1 GGDEF domain-containing protein -
PWA19_RS13815 (PWA19_13815) 2759717..2760112 - 396 Protein_2700 DUF977 family protein -
PWA19_RS13820 (PWA19_13820) 2760125..2760235 - 111 Protein_2701 replication protein -
PWA19_RS13825 (PWA19_13825) 2760236..2760597 + 362 Protein_2702 recombinase RecT -
PWA19_RS13830 (PWA19_13830) 2760596..2760904 + 309 Protein_2703 tyrosine-type recombinase/integrase -
- 2761023..2761166 + 144 - - Antitoxin
- 2761025..2761127 - 103 - - Toxin
PWA19_RS13835 (PWA19_13835) 2761268..2761621 - 354 WP_000722366.1 YebY family protein -
PWA19_RS13840 (PWA19_13840) 2761638..2762513 - 876 WP_000979693.1 copper homeostasis membrane protein CopD -
PWA19_RS13845 (PWA19_13845) 2762514..2762888 - 375 WP_001681742.1 CopC domain-containing protein YobA -
PWA19_RS13850 (PWA19_13850) 2763026..2763256 + 231 WP_000856224.1 DNA polymerase III subunit theta -
PWA19_RS13855 (PWA19_13855) 2763364..2764020 + 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
PWA19_RS13860 (PWA19_13860) 2764044..2764742 + 699 WP_000944282.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2742755..2766830 24075


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T273154 NZ_CP118536:c2761127-2761025 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT273154 NZ_CP118536:2761023-2761166 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References