Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 5656828..5657347 Replicon chromosome
Accession NZ_CP118152
Organism Pseudomonas chlororaphis strain ATCC 336631

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PUP64_RS25970 Protein ID WP_081360541.1
Coordinates 5657066..5657347 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1H3UB71
Locus tag PUP64_RS25965 Protein ID WP_009044432.1
Coordinates 5656828..5657076 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP64_RS25945 (PUP64_25945) 5652349..5652810 - 462 WP_009049642.1 YccF domain-containing protein -
PUP64_RS25950 (PUP64_25950) 5652883..5654646 - 1764 WP_081360538.1 hypothetical protein -
PUP64_RS25955 (PUP64_25955) 5654860..5655858 - 999 WP_081360539.1 bile acid:sodium symporter family protein -
PUP64_RS25960 (PUP64_25960) 5655943..5656731 + 789 WP_081360540.1 helix-turn-helix transcriptional regulator -
PUP64_RS25965 (PUP64_25965) 5656828..5657076 + 249 WP_009044432.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUP64_RS25970 (PUP64_25970) 5657066..5657347 + 282 WP_081360541.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP64_RS25975 (PUP64_25975) 5657525..5659174 - 1650 WP_081360542.1 FMN-binding glutamate synthase family protein -
PUP64_RS25980 (PUP64_25980) 5659231..5659713 - 483 WP_009049637.1 acyl-CoA thioesterase -
PUP64_RS25985 (PUP64_25985) 5660029..5660820 - 792 WP_081360543.1 methyltransferase domain-containing protein -
PUP64_RS25990 (PUP64_25990) 5661453..5661725 - 273 WP_081360544.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10821.62 Da        Isoelectric Point: 10.5816

>T272884 WP_081360541.1 NZ_CP118152:5657066-5657347 [Pseudomonas chlororaphis]
MTYELEFSEKAWKEWQKLGPTLKEQFKKKLQERLVNPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQASKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8997.37 Da        Isoelectric Point: 4.4142

>AT272884 WP_009044432.1 NZ_CP118152:5656828-5657076 [Pseudomonas chlororaphis]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERENDPTIKVSLD
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1H3UB71

References