Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4314787..4315415 Replicon chromosome
Accession NZ_CP118152
Organism Pseudomonas chlororaphis strain ATCC 336631

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP64_RS19860 Protein ID WP_038576104.1
Coordinates 4315017..4315415 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PUP64_RS19855 Protein ID WP_081359896.1
Coordinates 4314787..4315017 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP64_RS19845 (PUP64_19845) 4310119..4313535 - 3417 WP_081359894.1 type I-F CRISPR-associated helicase Cas3f -
PUP64_RS19850 (PUP64_19850) 4313532..4314509 - 978 WP_081359895.1 type I-F CRISPR-associated endonuclease Cas1f -
PUP64_RS19855 (PUP64_19855) 4314787..4315017 + 231 WP_081359896.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PUP64_RS19860 (PUP64_19860) 4315017..4315415 + 399 WP_038576104.1 tRNA(fMet)-specific endonuclease VapC Toxin
PUP64_RS19865 (PUP64_19865) 4315473..4317422 - 1950 WP_081359897.1 alkaline phosphatase D family protein -
PUP64_RS19870 (PUP64_19870) 4317558..4318082 - 525 WP_081359898.1 hypothetical protein -
PUP64_RS19875 (PUP64_19875) 4318079..4318813 - 735 WP_081359899.1 alpha/beta hydrolase -
PUP64_RS19880 (PUP64_19880) 4318817..4319314 - 498 WP_081363157.1 PAAR domain-containing protein -
PUP64_RS19885 (PUP64_19885) 4319519..4319695 - 177 WP_164486677.1 hypothetical protein -
PUP64_RS19890 (PUP64_19890) 4319902..4320177 - 276 WP_038576112.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14886.17 Da        Isoelectric Point: 7.2433

>T272883 WP_038576104.1 NZ_CP118152:4315017-4315415 [Pseudomonas chlororaphis]
MLKYMLDTNICIFTIKNKPERVREAFNRQHGRLCISSVTLMELIYGAEKSAAPERNLSVIEGFVARLEVLAYDYEAAIHS
GQLRAELARAGTPIGPYDQLIAGHARSQGLVLVTNNVREFERVPGLRIEDWL

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8514.44 Da        Isoelectric Point: 4.2821

>AT272883 WP_081359896.1 NZ_CP118152:4314787-4315017 [Pseudomonas chlororaphis]
MEQGSVFKSNRSQAIRMPKAVALPDDVTRVDIVAVGRTRIITPAGEAWDSWFDGESVSADFMNERDQPAEQEREAF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References