Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2647718..2648303 Replicon chromosome
Accession NZ_CP118141
Organism Pseudomonas chlororaphis strain ATCC 17814

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP70_RS12275 Protein ID WP_053260473.1
Coordinates 2648010..2648303 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP70_RS12270 Protein ID WP_053260472.1
Coordinates 2647718..2648008 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP70_RS12260 (PUP70_12260) 2645233..2646615 + 1383 WP_053260470.1 efflux transporter outer membrane subunit -
PUP70_RS12265 (PUP70_12265) 2646734..2647321 + 588 WP_053260471.1 hypothetical protein -
PUP70_RS12270 (PUP70_12270) 2647718..2648008 - 291 WP_053260472.1 putative addiction module antidote protein Antitoxin
PUP70_RS12275 (PUP70_12275) 2648010..2648303 - 294 WP_053260473.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP70_RS12280 (PUP70_12280) 2648538..2649932 - 1395 WP_053260474.1 VOC family protein -
PUP70_RS12285 (PUP70_12285) 2650196..2651320 + 1125 WP_053260475.1 diguanylate cyclase -
PUP70_RS12290 (PUP70_12290) 2651414..2652658 + 1245 WP_053260476.1 M20/M25/M40 family metallo-hydrolase -
PUP70_RS12295 (PUP70_12295) 2652891..2653286 + 396 WP_007932579.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(9-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10846.56 Da        Isoelectric Point: 10.5107

>T272810 WP_053260473.1 NZ_CP118141:c2648303-2648010 [Pseudomonas chlororaphis]
MNYEILQTTVFARWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNMGAGYRLYFTVRGNTLIVLLLGGDK
STQPADICQARYLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10197.74 Da        Isoelectric Point: 8.0096

>AT272810 WP_053260472.1 NZ_CP118141:c2648008-2647718 [Pseudomonas chlororaphis]
MSDTLLAFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References