Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1215368..1215906 Replicon chromosome
Accession NZ_CP118141
Organism Pseudomonas chlororaphis strain ATCC 17814

Toxin (Protein)


Gene name relE Uniprot ID A0A285H8D2
Locus tag PUP70_RS05365 Protein ID WP_009042149.1
Coordinates 1215628..1215906 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PUP70_RS05360 Protein ID WP_053259626.1
Coordinates 1215368..1215631 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP70_RS05345 (PUP70_05345) 1211357..1213630 - 2274 WP_053259624.1 TonB-dependent siderophore receptor -
PUP70_RS05350 (PUP70_05350) 1213837..1214517 + 681 WP_009042146.1 Fe2+-dependent dioxygenase -
PUP70_RS05355 (PUP70_05355) 1214521..1215306 + 786 WP_053259625.1 tetratricopeptide repeat protein -
PUP70_RS05360 (PUP70_05360) 1215368..1215631 + 264 WP_053259626.1 ribbon-helix-helix domain-containing protein Antitoxin
PUP70_RS05365 (PUP70_05365) 1215628..1215906 + 279 WP_009042149.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP70_RS05370 (PUP70_05370) 1215981..1217144 - 1164 WP_009042150.1 type III PLP-dependent enzyme -
PUP70_RS05375 (PUP70_05375) 1217844..1219001 - 1158 WP_007923834.1 ABC transporter ATP-binding protein -
PUP70_RS05380 (PUP70_05380) 1218998..1219651 - 654 WP_053259627.1 ABC transporter permease -
PUP70_RS05385 (PUP70_05385) 1219666..1220559 - 894 WP_053259628.1 glycine betaine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10853.45 Da        Isoelectric Point: 8.5409

>T272808 WP_009042149.1 NZ_CP118141:1215628-1215906 [Pseudomonas chlororaphis]
VRELKWTSKALSDLARLFEFLAPVNRSVAARTVQSLTQAPDTLLTNPRIGEQLEEFQPRDVRRLLVGPYEMRYEIQDATL
YILRVWHVREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9769.19 Da        Isoelectric Point: 5.6088

>AT272808 WP_053259626.1 NZ_CP118141:1215368-1215631 [Pseudomonas chlororaphis]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDVGRVIDHQAVQAWAESLMSD
KPLPVPK

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285H8D2

Antitoxin

Source ID Structure

References