Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 441355..441871 Replicon chromosome
Accession NZ_CP118141
Organism Pseudomonas chlororaphis strain ATCC 17814

Toxin (Protein)


Gene name stbE Uniprot ID A0A285EY61
Locus tag PUP70_RS01980 Protein ID WP_009041601.1
Coordinates 441590..441871 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PUP70_RS01975 Protein ID WP_081002203.1
Coordinates 441355..441600 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP70_RS01950 (PUP70_01950) 437109..438113 + 1005 WP_053259189.1 aspartyl beta-hydroxylase -
PUP70_RS01955 (PUP70_01955) 438079..438837 - 759 WP_007932057.1 slipin family protein -
PUP70_RS01960 (PUP70_01960) 438839..440224 - 1386 WP_053259190.1 nodulation protein NfeD -
PUP70_RS01965 (PUP70_01965) 440448..440909 + 462 WP_053259191.1 YbaK/EbsC family protein -
PUP70_RS01970 (PUP70_01970) 441047..441292 + 246 WP_009041599.1 DUF2789 domain-containing protein -
PUP70_RS01975 (PUP70_01975) 441355..441600 + 246 WP_081002203.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PUP70_RS01980 (PUP70_01980) 441590..441871 + 282 WP_009041601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP70_RS01985 (PUP70_01985) 442003..442431 + 429 WP_053259193.1 MarR family transcriptional regulator -
PUP70_RS01990 (PUP70_01990) 442428..444512 + 2085 WP_053259194.1 FUSC family protein -
PUP70_RS01995 (PUP70_01995) 444509..444718 + 210 WP_007932080.1 DUF1656 domain-containing protein -
PUP70_RS02000 (PUP70_02000) 444715..445611 + 897 WP_053259195.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10879.81 Da        Isoelectric Point: 10.5797

>T272806 WP_009041601.1 NZ_CP118141:441590-441871 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8843.18 Da        Isoelectric Point: 4.7164

>AT272806 WP_081002203.1 NZ_CP118141:441355-441600 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLSSAQGGPVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285EY61

Antitoxin

Source ID Structure

References