Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 716975..717632 Replicon chromosome
Accession NZ_CP117993
Organism Enterobacter hormaechei isolate 1023017620-1

Toxin (Protein)


Gene name cptA Uniprot ID A0A179PSF7
Locus tag PUO93_RS04215 Protein ID WP_017382887.1
Coordinates 717222..717632 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag PUO93_RS04210 Protein ID WP_003863437.1
Coordinates 716975..717241 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUO93_RS04190 712381..713814 - 1434 WP_017382891.1 6-phospho-beta-glucosidase BglA -
PUO93_RS04195 713931..714662 - 732 WP_015571796.1 MurR/RpiR family transcriptional regulator -
PUO93_RS04200 714929..715588 + 660 WP_003863433.1 hemolysin III family protein -
PUO93_RS04205 715700..716680 - 981 WP_017692714.1 tRNA-modifying protein YgfZ -
PUO93_RS04210 716975..717241 + 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
PUO93_RS04215 717222..717632 + 411 WP_017382887.1 protein YgfX Toxin
PUO93_RS04220 717634..718155 - 522 WP_015571793.1 flavodoxin FldB -
PUO93_RS04225 718257..719153 + 897 WP_003863442.1 site-specific tyrosine recombinase XerD -
PUO93_RS04230 719182..719895 + 714 WP_003863443.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PUO93_RS04235 719901..721634 + 1734 WP_017382886.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16321.21 Da        Isoelectric Point: 11.4775

>T272653 WP_017382887.1 NZ_CP117993:717222-717632 [Enterobacter hormaechei]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMMGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT272653 WP_003863437.1 NZ_CP117993:716975-717241 [Enterobacter hormaechei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A179PSF7

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References