Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sezT-pezA/zeta(toxin)
Location 245950..247017 Replicon chromosome
Accession NZ_CP117967
Organism Veillonella rogosae strain AC2811 AN NA

Toxin (Protein)


Gene name sezT Uniprot ID -
Locus tag PT376_RS01015 Protein ID WP_274204755.1
Coordinates 246157..247017 (+) Length 287 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID -
Locus tag PT376_RS01010 Protein ID WP_274204754.1
Coordinates 245950..246072 (+) Length 41 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT376_RS00985 241193..242179 - 987 WP_009351075.1 GMP reductase -
PT376_RS00990 242378..242908 + 531 WP_009351003.1 energy-coupled thiamine transporter ThiT -
PT376_RS00995 242901..244025 + 1125 WP_274204752.1 molybdopterin-guanine dinucleotide biosynthesis protein MobB -
PT376_RS01000 244006..245241 + 1236 WP_274204753.1 molybdopterin molybdotransferase MoeA -
PT376_RS01005 245543..245878 + 336 WP_009351084.1 cupin domain-containing protein -
PT376_RS01010 245950..246072 + 123 WP_274204754.1 hypothetical protein Antitoxin
PT376_RS01015 246157..247017 + 861 WP_274204755.1 zeta toxin family protein Toxin
PT376_RS01020 247032..248063 + 1032 WP_274204756.1 AraC family transcriptional regulator -
PT376_RS01025 248439..248705 + 267 WP_274204757.1 SemiSWEET family transporter -
PT376_RS01030 248886..249527 + 642 WP_054746889.1 hypothetical protein -
PT376_RS01035 249578..250606 + 1029 WP_265138665.1 AraC family transcriptional regulator -
PT376_RS01040 250992..251894 + 903 WP_054746885.1 L(+)-tartrate dehydratase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(60-245)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 287 a.a.        Molecular weight: 31988.56 Da        Isoelectric Point: 6.0550

>T272569 WP_274204755.1 NZ_CP117967:246157-247017 [Veillonella rogosae]
MVKLENTIKESLTQASHDISDVKAVKETSDVQAIESYSSEDFEKALERTIDFLTFNKNISSTPRAVILGGQSGAGKTTIH
RVKMLESKGNYIVIDGDTYRAQHPYFRELQEKYGVDSVDYTKMFAGKMVEAVIDKLSSLKYNLIIEGTLRSAAVPINTAT
LLKSKGYTVDFCLIATKPELSYLTTQLRYLEMMSVDPLQARATPKEHHDGIVKSLVANITELEQSGLFESLLVYKRNLEQ
VYNSKLCTESVGTVVEQILFGPWTKDESTLLEVSKSQEQALRAKLP

Download         Length: 861 bp

Antitoxin


Download         Length: 41 a.a.        Molecular weight: 4485.07 Da        Isoelectric Point: 3.7857

>AT272569 WP_274204754.1 NZ_CP117967:245950-246072 [Veillonella rogosae]
MNVVEQYNLTLQIEVLKEQSAETLARLCNLVEESGTSDCI

Download         Length: 123 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References