Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 5094747..5095376 Replicon chromosome
Accession NZ_CP117876
Organism Paenibacillus sp. KACC 21273

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PQ460_RS22375 Protein ID WP_274171229.1
Coordinates 5094747..5095073 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PQ460_RS22380 Protein ID WP_274171230.1
Coordinates 5095134..5095376 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQ460_RS22345 (PQ460_22345) 5091841..5092065 + 225 WP_069329692.1 hypothetical protein -
PQ460_RS22350 (PQ460_22350) 5092211..5092555 - 345 WP_274171227.1 hypothetical protein -
PQ460_RS22355 (PQ460_22355) 5092754..5092927 - 174 WP_273614470.1 hypothetical protein -
PQ460_RS22360 (PQ460_22360) 5093160..5093405 - 246 WP_274171228.1 hypothetical protein -
PQ460_RS22365 (PQ460_22365) 5093544..5093987 + 444 WP_273614469.1 DUF6376 family protein -
PQ460_RS22370 (PQ460_22370) 5094223..5094555 - 333 WP_273614468.1 hypothetical protein -
PQ460_RS22375 (PQ460_22375) 5094747..5095073 - 327 WP_274171229.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PQ460_RS22380 (PQ460_22380) 5095134..5095376 - 243 WP_274171230.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PQ460_RS22385 (PQ460_22385) 5095517..5098612 - 3096 WP_274171231.1 efflux RND transporter permease subunit -
PQ460_RS22390 (PQ460_22390) 5098614..5100089 - 1476 WP_274171232.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-107)

Antitoxin

SpoVT-AbrB domain

(6-47)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12376.32 Da        Isoelectric Point: 6.9662

>T272452 WP_274171229.1 NZ_CP117876:c5095073-5094747 [Paenibacillus sp. KACC 21273]
MSYIPSQGDIIYLDFNPTKGYEQAGHRPAVVVSNNEFHRTGMMMVVPVTNTIQRHPLHIHLNEDNKIKGKIMCEQMKSLD
YKARSPYKVDVLPSSILEEVIEIIQSCF

Download         Length: 327 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9165.39 Da        Isoelectric Point: 5.8597

>AT272452 WP_274171230.1 NZ_CP117876:c5095376-5095134 [Paenibacillus sp. KACC 21273]
MRGTVKKWGNSQGVRLPKSILEEAHIKENDEVEFYVVDGIIQIKAVKQPITLKERFASYTTEELKSSEWDTGSPQGKEVW

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References