Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 2002310..2002847 Replicon chromosome
Accession NZ_CP117811
Organism Lentisphaera profundi strain SAORIC-696

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PQO03_RS08050 Protein ID WP_274149384.1
Coordinates 2002578..2002847 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PQO03_RS08045 Protein ID WP_274149383.1
Coordinates 2002310..2002585 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQO03_RS08025 (PQO03_08025) 1999124..1999264 + 141 WP_274149377.1 hypothetical protein -
PQO03_RS08030 (PQO03_08030) 1999403..1999768 + 366 WP_274149378.1 BlaI/MecI/CopY family transcriptional regulator -
PQO03_RS08035 (PQO03_08035) 1999765..2001324 + 1560 WP_274149379.1 M56 family metallopeptidase -
PQO03_RS08040 (PQO03_08040) 2001633..2002154 + 522 WP_274149381.1 MerC domain-containing protein -
PQO03_RS08045 (PQO03_08045) 2002310..2002585 + 276 WP_274149383.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PQO03_RS08050 (PQO03_08050) 2002578..2002847 + 270 WP_274149384.1 type II toxin-antitoxin system YafQ family toxin Toxin
PQO03_RS08055 (PQO03_08055) 2003151..2004188 + 1038 WP_274149385.1 C-type lectin domain-containing protein -
PQO03_RS08060 (PQO03_08060) 2005293..2006390 - 1098 WP_274149387.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - fcl 227..2808340 2808113


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-82)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10361.00 Da        Isoelectric Point: 8.8337

>T272280 WP_274149384.1 NZ_CP117811:2002578-2002847 [Lentisphaera profundi]
MLELVYGSQFKKDFKKARKLPIEDLSNIFKIISTLQSQTPLDQKYKDHDLTGNYKAYRECHIKPDLLLIYTVDGKDLSLV
RIGSHSELF

Download         Length: 270 bp

>T272280 NZ_CP117811:2002578-2002847 [Lentisphaera profundi]
ATGCTTGAACTCGTATATGGTAGTCAATTCAAAAAGGATTTTAAGAAAGCTCGTAAGCTTCCGATTGAAGATTTAAGCAA
CATTTTCAAAATCATATCGACACTTCAAAGTCAAACGCCTTTAGACCAAAAGTACAAAGACCATGATCTAACTGGAAACT
ATAAAGCTTATCGGGAATGTCATATTAAACCCGACCTACTTTTAATTTATACAGTCGATGGTAAAGATTTATCATTGGTT
AGAATCGGGTCTCATTCAGAATTATTTTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10037.49 Da        Isoelectric Point: 4.7961

>AT272280 WP_274149383.1 NZ_CP117811:2002310-2002585 [Lentisphaera profundi]
MKTELISTRIEHDLKVEFTNICDDLGLSPSQAIKLFAKAVINYGGIPFQLKVKQPNAVTRQAMEELESGKGTRVKDATEL
FSDLGVDIQDA

Download         Length: 276 bp

>AT272280 NZ_CP117811:2002310-2002585 [Lentisphaera profundi]
ATGAAAACGGAATTGATTAGTACTAGAATCGAACATGACTTAAAAGTTGAGTTCACCAACATCTGTGATGATTTAGGTTT
AAGTCCATCACAAGCTATTAAACTGTTTGCTAAAGCTGTTATCAACTATGGCGGTATTCCCTTCCAGTTAAAAGTTAAGC
AACCTAACGCTGTAACTCGTCAAGCTATGGAAGAGTTAGAAAGTGGCAAGGGAACTAGAGTCAAGGATGCCACAGAACTA
TTCAGTGACTTGGGTGTAGATATTCAGGATGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References